Pathology Faculty Member

More information on...

  • Home
  • Training
  • Research
  • Clinical Services
  • Expert Consultation
  • Faculty
  • Contact Information:

    Experimental Pathology
    Yerkes Primate Research Center, Room 1026
    Atlanta, GA. 30329
    404-727-8587 Phone

    For an expert Pathology consultation,
    or to send a specimen, call:

    1-404-712-5947


    Eric Hunter, PhD

    HIV Pathogenesis
    Vaccines

    Professor
    Pathology & Laboratory Medicine


    Pathology Faculty Photo

    Other Appointments/Positions

    Professor of Microbiology and Immunology, Emory University

    Senior Scientist Co-Director, Emory Center for AIDS Research, Emory University

    Co-Director for Basic and Translational Science, Emory Center for AIDS Research, Emory University


    Pathology Division(s):
    Experimental Pathology


    Email Address:
    eric.hunter2@emory.edu


    Education:

    B.Sc. (Honors)   Birmingham University, Birmingham, England Field of Study- Bacteriology, 1966 - 1969

    Ph.D.   Imperial Cancer Research Fund & Brunel University of England--- Field of Study - Tumor Immunology, 1969 - 1972

    Postdoctoral Fellow   Postdoctoral Fellow, University of Southern California, Los Angeles-- Field of Study - RNA TUmor Virus, 1972 - 1976



    Research Interests:

    - Molecular Biology of HIV and other Retroviruses
    Research in my laboratory centers on the replication and pathogenesis of retroviruses, with a particular focus on the development of novel therapeutic and vaccine approaches to HIV. Using a model system based on the primate retrovirus Mason-Pfizer monkey virus (M-PMV), we are studying the viral-host interactions that are necessary for assembly of virions. These studies have identified unique insights into the mechanisms the virus employs for intracellular targeting of components necessary for the assembly and release of infectious virions.


    - HIV-1 Glycoprotein-mediated Entry
    Over the past several years, our laboratory has characterized the biosynthesis and transport of the HIV-1 glycoprotein (Env), and has identified protein domains critical for fusion and entry of the virus. Our current studies focus on the membrane-spanning component of the Env complex, gp41, which not only acts as the membrane fusion machine for the virus, but also targets Env to the site of virus assembly. These studies utilize molecular genetics approaches to dissect out structure-function relationships within the protein, with the goal of identifying new therapeutic targets for HIV-1.


    - Heterosexual Transmission of HIV-1
    Employing knowledge and technology gained in the molecular characterization of the HIV Env complex and its role in membrane fusion, we have embarked on studies in Rwanda and Zambia aimed at defining, at a molecular level, the nature of the virus that establishes infection following heterosexual transmission. Studies from more than 20 transmission pairs show that a severe genetic bottleneck occurs during transmission, with a single genetic variant initiating infection in the new host. Studies are ongoing to define the unique biological and structural properties of the transmitted virus with the goal of targeting these variants with vaccines. We are also investigating how HIV-1 adapts over time to cellular and humoral immune pressures as it is transmitted from one immunogenetic environment to another. These studies will provide keys to the mechanisms HIV uses to evade the immune response of a newly infected host.



    Honors / Awards:

    Ohio State University, Distinguished Research Career Award, 2004

    Georgia Research Alliance Eminent Scholar, 2004

    University of Alabama at Birmingham, Distinguished Faculty Lecturer Award, 2002

    Senior Fellowship, Fogarty International, 1994 - 1995

    National Institute of Allergy and Infectious Diseases Merit Award for Structure/Function Analysis of the HIV Env Gene Product, 1992 - 2002

    National Cancer Institute Merit Award for Genetics of Type D Retroviruses, 1991 - 2000

    National Cancer Institute Merit Award for Site Specific Mutagenesis in the Env Gene of Rous Sarcoma Virus, 1989 - 1997

    National Cancer Institute Research Career Development Award, 1980 - 1985

    Postdoctoral Fellow of the Damon Runyon Memorial Fund for Cancer Research, 1975

    Cancer Immunology Fellow of the Cancer Research Institute, New York, 1972

    Selected Publications:

    Published and Accepted Research Articles -

    Prentice HA, Price MA, Porter TR, Cormier E, Mugavero MJ, Kamali A, Karita E, Lakhi S, Sanders EJ, Anzala O, Amornkul PN, Allen S, HUNTER E, Kaslow RA, Gilmour J, Tang J, Partnership IAHP. (2014). Dynamics of viremia in primary HIV-1 infection in Africans: Insights from analyses of host and viral correlates. Virology. 449:254-62. PMCID: PMC3931417


    Carlson JM, Schaefer M, Monaco DC, Batorsky R, Claiborne DT, Prince J, Deymier MJ, Ende ZS, Klatt NR, DeZiel CE, Lin TH, Peng J, Seese AM, Shapiro R, Frater J, Ndung'u T, Tang J, Goepfert P, Gilmour J, Price MA, Kilembe W, Heckerman D, Goulder PJ, Allen TM, Allen S, HUNTER E. (2014). HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck. Science. 345(6193):1254031. PMID: 25013080


    Penezina O, Krueger NX, Rodriguez-Chavez IR, Busch MP, Hural J, Kim JH, O'Connell RJ, HUNTER E, Aboud S, Higgins K, Kovalenko V, Clapham D, Crane D, Levin AE, Group HIVSS. (2014). Performance of a redesigned HIV Selectest enzyme-linked immunosorbent assay optimized to minimize vaccine-induced seropositivity in HIV vaccine trial participants. Clinical and vaccine immunology : CVI. 21(3):391-8. PMCID: PMC3957658.


    Cavrois M, Neidleman J, Santiago ML, Derdeyn CA, HUNTER E, Greene WC. (2014). Enhanced Fusion and Virion Incorporation for HIV-1 Subtype C Envelope Glycoproteins with Compact V1/V2 Domains. J Virol. 88(4):2083-94. PMCID: PMC3911571.


    Prentice HA, Pajewski NM, He D, Zhang K, Brown EE, Kilembe W, Allen S, HUNTER E, Kaslow RA, Tang J. (2014). Host genetics and immune control of HIV-1 infection: fine mapping for the extended human MHC region in an African cohort. Genes and immunity. 15(5):275-81. PMCID: PMC4111776


    Claiborne DT, Prince JL, HUNTER E. (2014). A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses. Journal of visualized experiments : JoVE. (90). PMID: 25225725.


    Deymier MJ, Claiborne DT, Ende Z, Ratner HK, Kilembe W, Allen S, HUNTER E. (2014). Particle infectivity of HIV-1 full-length genome infectious molecular clones in a subtype C heterosexual transmission pair following high fidelity amplification and unbiased cloning. Virology. 468-470C:454-61. PMID: 25243334


    Payne RP, Branch S, Kloverpris H, Matthews PC, Koofhethile CK, Strong T, Adland E, Leitman E, Frater J, Ndung'u T, HUNTER E, Haubrich R, Mothe B, Edwards A, Riddell L, Chen F, Harrigan PR, Brumme ZL, Mallal S, John M, Jooste JP, Shapiro R, Deeks SG, Walker BD, Brander C, Landis C, Carlson JM, Prado JG, Goulder PJ. (2014). Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints. Journal of virology. 88(9):4668-78. PMCID: PMC3993828


    Wen X, Ding L, HUNTER E, Spearman P. (2014). An siRNA Screen of Membrane Trafficking Genes Highlights Pathways Common to HIV-1 and M-PMV Virus Assembly and Release. PloS one. 9(9):e106151. PMCID: PMC4154853


    Pereira LE, Clark J, Grznarova P, Wen X, LaCasse R, Ruml T, Spearman P, HUNTER E. (2014). Direct evidence for intracellular anterograde co-transport of M-PMV Gag and Env on microtubules. Virology. 449:109-19. PMID: 24418544


    Wen X, Ding L, Wang JJ, Qi M, Hammonds J, Chu H, Chen X, HUNTER E, Spearman P. (2014). ROCK1 and LIM Kinase Modulate Retrovirus Particle Release and Cell-Cell Transmission Events. Journal of virology. 88(12):6906-21. PMCID: PMC4054354


    Basu D, Xiao P, Ende Z, Bere A, Britt WJ, Mulenga J, Kilembe W, Allen SA, Derdeyn CA, HUNTER E. (2014). Low antibody-dependent cellular cytotoxicity responses in Zambians prior to HIV-1 intrasubtype C superinfection. Virology. 462-463C:295-8. PMCID: PMC4125417


    Fauci AS, Marovich MA, Dieffenbach CW, HUNTER E, Buchbinder SP. (2014). Immunology. Immune activation with HIV vaccines. Science. 344(6179):49-51. PMID: 24700849


    Li X, Price MA, He D, Kamali A, Karita E, Lakhi S, Sanders EJ, Anzala O, Amornkul PN, Allen S, HUNTER E, Kaslow RA, Gilmour J, Tang J, Partnership IAHP. (2014). Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions. Human genetics. 133(9):1187-97. PMCID: PMC4127002


    Prentice HA, Porter TR, Price MA, Cormier E, He D, Farmer PK, Kamali A, Karita E, Lakhi S, Sanders EJ, Anzala O, Amornkul PN, Allen S, HUNTER E, R. Kaslow A, Gilmour J, Tang J, for the IAVI African Prevention Partnership. (2013). HLA-B*57 versus HLA-B*81 in HIV-1 Infection: Slow and Steady Wins the Race? Journal of virology. PMCID: PMC3624227.


    Murphy MK, Yue L, Pan R, Boliar S, Sethi A, Tian J, Pfafferot K, Karita E, Allen SA, Cormier E, Goepfert PA, Borrow P, Robinson JE, Gnanakaran S, HUNTER E, Kong XP, Derdeyn CA. (2013). Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth. PLoS pathogens. 9(2):e1003173. PMCID: PMC3585129.


    Kraft CS, Basu D, Hawkins PA, Hraber PT, Chomba E, Mulenga J, Kilembe W, Khu NH, Derdeyn CA, Allen SA, Manigart O, HUNTER E. (2012). Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses. Retrovirology. 9:22. PMCID: PMC3349552.


    Garber DA, O'Mara LA, Gangadhara S, McQuoid M, Zhang X, Zheng R, Gill K, Verma M, Yu T, Johnson B, Li B, Derdeyn CA, Ibegbu C, Altman JD, HUNTER E, Feinberg MB. (2012). Deletion of Specific Immune-Modulatory Genes from Modified Vaccinia Virus Ankara-Based HIV Vaccines Engenders Improved Immunogenicity in Rhesus Macaques. Journal of virology. 86(23):12605-15. PMCID: PMC3497691.


    Prchal J, Srb P, HUNTER E, Ruml T, Hrabal R. (2012). The structure of myristoylated Mason-Pfizer monkey virus matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in its membrane binding. Journal of molecular biology. 423(3):427-38. PMCID: PMC3579217.


    Baalwa J, Wang S, Parrish NF, Decker JM, Keele BF, Learn GH, Yue L, Ruzagira E, Ssemwanga D, Kamali A, Amornkul PN, Price MA, Kappes JC, Karita E, Kaleebu P, Sanders E, Gilmour J, Allen S, HUNTER E, Montefiori DC, Haynes BF, Cormier E, Hahn BH, Shaw GM. (2013). Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones. Virology. 436(1):33-48. PMCID: PMC3545109.


    Basu D, Kraft CS, Murphy MK, Campbell PJ, Yu T, Hraber PT, Irene C, Pinter A, Chomba E, Mulenga J, Kilembe W, Allen SA, Derdeyn CA, HUNTER E. (2012). HIV-1 subtype C superinfected individuals mount low autologous neutralizing antibody responses prior to intrasubtype superinfection. Retrovirology. 9:76. PMCID: PMC3477039.


    Matthews PC, Koyanagi M, Kloverpris HN, Harndahl M, Stryhn A, Akahoshi T, Gatanaga H, Oka S, Juarez Molina C, Valenzuela Ponce H, Avila Rios S, Cole D, Carlson J, Payne RP, Ogwu A, Bere A, Ndung'u T, Gounder K, Chen F, Riddell L, Luzzi G, Shapiro R, Brander C, Walker B, Sewell AK, Reyes Teran G, Heckerman D, HUNTER E, Buus S, Takiguchi M, Goulder PJ. (2012). Differential Clade-Specific HLA-B*3501 Association with HIV-1 Disease Outcome Is Linked to Immunogenicity of a Single Gag Epitope. Journal of virology. 86(23):12643-54. PMCID: PMC3497693.


    Prince JL, Claiborne DT, Carlson JM, Schaefer M, Yu T, Lahki S, Prentice HA, Yue L, Vishwanathan SA, Kilembe W, Goepfert P, Price MA, Gilmour J, Mulenga J, Farmer P, Derdeyn CA, Tang J, Heckerman D, Kaslow RA, Allen SA, HUNTER E. (2012). Role of Transmitted Gag CTL Polymorphisms in Defining Replicative Capacity and Early HIV-1 Pathogenesis. PLoS pathogens. 8(11):e1003041. PMCID: PMC3510241.


    Shaw GM, HUNTER E. (2012). HIV Transmission. Cold Spring Harbor perspectives in medicine. 2(11). PMID: 23043157.


    Yue L, Prentice HA, Farmer P, Song W, He D, Lakhi S, Goepfert P, Gilmour J, Allen S, Tang J, Kaslow RA, HUNTER E. (2013). Cumulative Impact of Host and Viral Factors on HIV-1 Viral Load Control during Early Infection. Journal of virology. 87(2):708-15. PMCID: PMC3554094


    Wright JK, Naidoo VL, Brumme ZL, Prince JL, Claiborne DT, Goulder PJ, Brockman MA, HUNTER E, Ndung'u T. (2012). Impact of HLA-B*81-associated mutations in HIV-1 Gag on viral replication capacity. J Virol. 86(6):3193-9. PMCID: PMC3302318.


    Sullivan PS, Fideli U, Wall KM, Chomba E, Vwalika C, Kilembe W, Tichacek A, Luisi N, Mulenga J, HUNTER E, Boeras D, Allen S. (2012). Prevalence of seroconversion symptoms and relationship to set-point viral load: findings from a subtype C epidemic, 1995-2009. Aids. 26(2):175-84. PMCID: PMC3589587.


    Merino AM, Song W, He D, Mulenga J, Allen S, HUNTER E, Tang J, Kaslow RA. (2012). HLA-B signal peptide polymorphism influences the rate of HIV-1 acquisition but not viral load. J Infect Dis. 205(12):1797-805. PMID: PMC22492862.


    Manigart O, Boeras DI, Karita E, Hawkins PA, Vwalika C, Makombe N, Mulenga J, Derdeyn CA, Allen S, HUNTER E. (2012). A gp41-Based Heteroduplex Mobility Assay Provides Rapid and Accurate Assessment of Intrasubtype Epidemiological Linkage in HIV Type 1 Heterosexual Transmission Pairs. AIDS Res Hum Retroviruses. PMCID: PMC3505061.


    Kilembe W, Keeling M, Karita E, Lakhi S, Chetty P, Price MA, Makkan H, Latka M, Likoti M, Ilukui K, Hurlston M, Allen S, Stevens G, HUNTER E. (2012). Failure of A Novel, Rapid Antigen and Antibody Combination Test to Detect Antigen-Positive HIV Infection in African Adults with Early HIV Infection. PLoS One. 7(6):e37154. PMCID: PMC3371037.


    Hu L, Song W, Brill I, Mulenga J, Allen S, HUNTER E, Shrestha S, Tang J, Kaslow RA. (2012). Genetic variations and heterosexual HIV-1 infection: analysis of clustered genes encoding CC-motif chemokine ligands. Genes Immun. 13(2):202-5. PMCID: PMC3559129.


    Merino A, Malhotra R, Morton M, Mulenga J, Allen S, HUNTER E, Tang J, Kaslow RA. (2011). Impact of a functional KIR2DS4 allele on heterosexual HIV-1 transmission among discordant Zambian couples. J Infect Dis. 203:487-495. PMCID: PMC3071217


    Boeras DI, Luisi N, Karita E, McKinney S, Sharkey T, Keeling M, Chomba E, Kraft C, Wall K, Bizimana J, Kilembe W, Tichacek A, Caliendo AM, HUNTER E, Allen S. (2011). Indeterminate and discrepant rapid HIV test results in couples' HIV testing and counselling centres in Africa. J Int AIDS Soc. 14:18-30. PMCID: PMC3086828


    Malhotra R, Hu L, Song W, Brill I, Mulenga J, Allen S, HUNTER E, Shrestha S, Tang J, Kaslow RA. (2011). Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians. Retrovirology. 8:22. PMCID: PMC3075214.


    Song W, He D, Brill I, Malhotra R, Mulenga J, Allen S, HUNTER E, Tang J, Kaslow RA. (2011). Disparate Associations of HLA Class I Markers with HIV-1 Acquisition and Control of Viremia in an African Population. PLoS One. 6(8):e23469. PMCID: PMC3157381


    Makarova N, Zhao C, Zhang Y, Bhosle S, Suppiah S, Rhea JM, Kozyr N, Arnold RS, Ly H, Molinaro RJ, Parslow TG, HUNTER E, Liotta D, Petros J, Blackwell JL. (2011). Antibody responses against xenotropic murine leukemia virus-related virus envelope in a murine model. PLoS One. 6(4):e18272. PMCID: PMC3071813.


    Boeras DI, Hraber PT, Hurlston M, Evans-Strickfaden T, Bhattachary T, Giorgi EE, Mulenga J, Karita E, Korber BT, Allen S, Hart CE, Derdeyn CA, and HUNTER E. (2011). Role of donor genital tract HIV-1 diversity in the transmission bottleneck. Proc. Nat. Acad. Sci. USA. 108(46), E1156-63. PMCID: PMC3219102


    Crawford H, Matthews PC, Schaefer M, Carlson JM, Leslie A, Kilembe W, Allen S, Ndung'u T, Heckerman D, HUNTER E, Goulder PJ. (2011). The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms. J Virol. 85:1384-1390. PMCID: PMC3020512


    Cavrois, M., J. Neidleman, N. Galloway, C. A. Derdeyn, E. HUNTER, and W. C. Greene. (2011) Measuring HIV fusion mediated by envelopes from primary viral isolates. Methods. 53(1):34-8. PubMed Central PMCID: PMC3563671.


    Tang J, Cormier E, Gilmour J, Price MA, Prentice HA, Song W, Kamali A, Karita E, Lakhi S, Sanders EJ, Anzala O, Amornkul PN, Allen S, HUNTER E, Kaslow RA. (2011) Human leukocyte antigen variants B*44 and B*57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub-Saharan Africans with several viral subtypes. J Virol. 85:8894-8902. PMCID: PMC3165830


    Addo MM, Altfeld M, Brainard DM, Rathod A, Piechocka-Trocha A, Fideli U, Mulenga J, Shutes E, Alvino DM, HUNTER E, Allen SA, Walker BD. (2011). Lack of detectable HIV-1-specific CD8(+) T cell responses in Zambian HIV-1-exposed seronegative partners of HIV-1-positive individuals. J Infect Dis. 203:258-262. PMCID: PMC3071055


    Price MA, Wallis CL, Lakhi S, Karita E, Kamali A, Anzala O, Sanders EJ, Bekker LG, Twesigye R, HUNTER E, Kaleebu P, Kayitenkore K, Allen S, Ruzagira E, Mwangome M, Mutua G, Amornkul PN, Stevens G, Pond SL, Schaefer M, Papathanasopoulos MA, Stevens W, Gilmour J. (2011) Transmitted HIV type 1 drug resistance among individuals with recent HIV infection in East and Southern Africa. AIDS Res Hum Retroviruses,27:5-12. PMCID: PMC3045073.


    Bhakta SJ, Shang L, Prince JL, Claiborne DT, HUNTER E. (2011). Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity. Retrovirology. 8:37. PMCID: PMC3117779.


    Bhosle, S., S. Suppiah, R. Molinaro, Y. Liang, R. Arnold, W. Diehl, N. Makarova, J. Blackwell, J. Petros, D. Liotta, E. HUNTER, and H. Ly. (2010). Evaluation of cellular determinants required for in vitro xenotropic murine leukemia virus-related virus entry into human prostate cancer and noncancerous cells. J Virol 84:6288-96. PMCID: PMC2903252


    Shang L, HUNTER, E. (2010). Residues in the membrane-spanning domain core modulate conformation and fusogenicity of the HIV-I envelope glycoprotein. Virology. 404:158-67. PMCID: PMC2902644


    Alexander M, Lynch R, Mulenga J, Allen S, Derdeyn CA, HUNTER E. (2010). Donor and recipient envs from heterosexual human immunodeficiency virus subtype C transmission pairs require high receptor levels for entry. J Virol. PMCID: PMC2849512


    Arnold, R. S., N. V. Makarova, A. O. Osunkoya, S. Suppiah, T. A. Scott, N. A. Johnson, S. M. Bhosle, D. Liotta, E. HUNTER, F. F. Marshall, H. Ly, R. J. Molinaro, J. L. Blackwell, and J. A. Petros. (2010). XMRV infection in patients with prostate cancer: novel serologic assay and correlation with PCR and FISH. Urology 75(4):755-61. PMID: 20371060


    Bansal A, Carlson J, Yan J, Akinsiku OT, Schaefer M, Sabbaj S, Bet A, Levy DN, Heath S, Tang J, Kaslow RA, Walker BD, Ndung'u T, Goulder PJ, Heckerman D, HUNTER, E., Goepfert PA. (2010). CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription. J Exp Med. 207(1):51-9. PMCID: PMC2812545


    Khurana S, Norris PJ, Busch MP, Haynes BF, Park S, Sasono P, Mlisana K, Salim AK, Hecht FM, Mulenga J, Chomba E, HUNTER, E., Allen S, Nemo G, Rodriguez-Chavez IR, J. B. Margolick, and H. Golding. (2010). HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection. J Clin Microbiol. 48(1):281-5. PMCID: PMC2812287.


    Tang J, Malhotra R, Song W, Brill I, Hu L, Farmer PK, Mulenga J, Allen S, HUNTER E, Kaslow RA. (2010). Human leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationships. PLoS One. 5(3):e9629. PMCID: PMC2835758


    Rong R, Li B, Lynch RM, Haaland RE, Murphy MK, Mulenga J, Allen SA, Pinter A, Shaw GM, HUNTER, E., Robinson JE, Gnanakaran S, Derdeyn CA. (2009). Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways. PLoS Pathog 5(9):e1000594. PMCID: PMC2741593


    Isaacman-Beck, J., E. A. Hermann, Y. Yi, S. J. Ratcliffe, J. Mulenga, S. Allen, E. HUNTER, C. A. Derdeyn, and R. G. Collman. (2009). Heterosexual transmission of human immunodeficiency virus type 1 subtype C: Macrophage tropism, alternative coreceptor use, and the molecular anatomy of CCR5 utilization. J Virol 83:8208-20, PMCID: 2715751


    Kohoutová Z, Rumlová M, Andreánsky M, Sakalian M, HUNTER, E., Pichová I, Ruml T. (2009). The impact of altered polyprotein ratios on the assembly and infectivity of Mason-Pfizer monkey virus. Virology. 384(1):59-68. PMID: 19062065


    Yue, L., Shang, L., HUNTER, E. (2009). Truncation of the Membrane-spanning Domain of Human Immunodeficiency Virus Type I Envelope Glycoprotein Defines Elements Required for Fusion, Incorporation and Infectivity. J. Virol. 83(22): 11588-98. PMCID: PMC2772686


    Haaland, R. E., P. A. Hawkins, J. Salazar-Gonzalez, A. Johnson, A. Tichacek, E. Karita, O. Manigart, J. Mulenga, B. F. Keele, G. M. Shaw, B. H. Hahn, S. A. Allen, C. A. Derdeyn, and HUNTER, E. (2009). Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1. PLoS Pathog 5(1):e1000274. PMCID: 2621345


    Crawford, H., W. Lumm, A. Leslie, M. Schaefer, D. Boeras, J. G. Prado, J. Tang, P. Farmer, T. Ndung'u, S. Lakhi, J. Gilmour, P. Goepfert, B. D. Walker, R. Kaslow, J. Mulenga, S. Allen, P. J. Goulder, and HUNTER, E. (2009). Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients. J Exp Med 206(4):909-21, PMCID: 2715113


    Kawashima, Y., K. Pfafferott, J. Frater, P. Matthews, R. Payne, M. Addo, H. Gatanaga, M. Fujiwara, A. Hachiya, H. Koizumi, N. Kuse, S. Oka, A. Duda, A. Prendergast, H. Crawford, A. Leslie, Z. Brumme, C. Brumme, T. Allen, C. Brander, R. Kaslow, J. Tang, HUNTER, E., S. Allen, J. Mulenga, S. Branch, T. Roach, M. John, S. Mallal, A. Ogwu, R. Shapiro, J.G. Prado, O.G. Pybus, P. Klenerman, T. Ndung'u, R. Phillips, D. Heckerman, P.R. Harrigan, B.D. Walker, M. Takiguchi, and P. Goulder. (2009). Adaptation of HIV-1 to HLAI. Nature 458:641-5. PMCID: 3148020


    Salazar-Gonzalez, J. F., M. G. Salazar, B. F. Keele, G. H. Learn, E. E. Giorgi, H. Li, J. M. Decker, S. Wang, J. Baalwa, M. H. Kraus, N. F. Parrish, K. S. Shaw, M. B. Guffey, K. J. Bar, K. L. Davis, C. Ochsenbauer-Jambor, J. C. Kappes, M. S. Saag, M. S. Cohen, J. Mulenga, C. A. Derdeyn, S. Allen, E. HUNTER, M. Markowitz, P. Hraber, A. S. Perelson, T. Bhattacharya, B. F. Haynes, B. T. Korber, B. H. Hahn, and G. M. Shaw. (2009). Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J Exp Med 206:1273-89, PMCID: 2715054


    Salazar-Gonzalez, J.F., E. Bailes, K.T. Pham, M.G. Salazar, M.B. Guffey, B.F. Keele, C.A. Derdeyn, P. Farmer, HUNTER, E., S. Allen, O. Manigart, J. Mulenga, J.A. Anderson, R. Swanstrom, B.F. Haynes, G.S. Athreya, B.T. Korber, P.M. Sharp, G.M. Shaw, and B.H. Hahn. (2008). Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing. J Virol 82:3952-70. PMCID: 2293010


    Derdeyn, C. A., and E. HUNTER. (2008). Viral characteristics of transmitted HIV. Curr Opin HIV AIDS 3:16-21. PMID: 19372939


    Goepfert, PA, W Lumm, P Farmer, P Matthews, A Prendergast, JM Carlson, CA Derdeyn, J Tang, RA Kaslow, A Bansal, K Yusim, D Heckerman, J Mulenga, SA Allen, P Goulder, and E. HUNTER. (2008). Transmission of HIV-1 Gag Immune Escape Mutations is Associated with Reduced Viral Load in Linked Recipients. J. Exp. Med. 205:1009-17. PMCID: 2373834


    Shang, L, L Yue, and HUNTER, E., (2008). Role of the Membrane-Spanning Domain of Human Immunodeficiency Virus type 1 Envelope Glycoprotein in Cell-Cell Fusion and Virus Infection. J Virol 82:5417-28. PMCID: 2395181


    Tang, J., W. Shao, Y.J. Yoo, I. Brill, J. Mulenga, S. Allen, HUNTER, E., and R.A. Kaslow. (2008). Human leukocyte antigen class I genotypes in relation to heterosexual HIV type 1 transmission within discordant couples. J Immunol 181:2626-35. PMCID: 2570252


    Vishwanathan, S.A. and HUNTER, E. (2008). Importance of the membrane-perturbing properties of the membrane-proximal external region of human immunodeficiency virus type 1 gp41 to viral fusion. J Virol 82:5118-5126. PMCID: 2395175


    Vishwanathan, S. A., A. Thomas, R. Brasseur, R. F. Epand, HUNTER, E., and R. M. Epand. (2008). Hydrophobic substitutions in the first residue of the CRAC segment of the gp41 protein of HIV. Biochemistry 47:124-30, PMID: 18081318.


    Vishwanathan, S. A., A. Thomas, R. Brasseur, R. F. Epand, HUNTER, E., and R. M. Epand. (2008). Large changes in the CRAC segment of gp41 of HIV do not destroy fusion activity if the segment interacts with cholesterol. Biochemistry 47:11869-76. NIHMSID: NIHMS86526, PMID: 18937430


    Vlach, J., J. Lipov, M. Rumlova, V. Veverka, J. Lang, P. Srb, Z. Knejzlik, I. Pichova, HUNTER, E., R. Hrabal, and T. Ruml. (2008). D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein. Proc Natl Acad Sci U S A 105:10565-70. PMCID: 2492450


    Wildova, M., R. Hadravova, J. Stokrova, I. Krizova, T. Ruml, HUNTER, E., I. Pichova, and M. Rumlova. (2008). The effect of point mutations within the N-terminal domain of Mason-Pfizer monkey virus capsid protein on virus core assembly and infectivity. Virology 380:157-63, PMID: 18755489


    Payne BA, Nsutebu EF, HUNTER E, Olarinde O, Collini P, Dunbar JA, Basta MS, Elston JW, Schmid ML, Thaker H, Chadwick DR. (2008). Low prevalence of transmitted antiretroviral drug resistance in a large UK HIV-1 cohort. The Journal of antimicrobial chemotherapy. 62(3):464-8. PMID: 18552342


    Diehl, W.E., E. Stansell, S.M. Kaiser, M. Emerman, and HUNTER, E. (2008). Identification of postentry restrictions to Mason-Pfizer monkey virus infection in New World monkey cells. J Virol 82:11140-11151. PMCID: 2573280


    Karita, E., M. Price, HUNTER, E., Chomba, S. Allen, L. Fei, A. Kamali, E. J. Sanders, O. Anzala, M. Katende, and N. Ketter. (2007). Investigating the utility of the HIV-1 BED capture enzyme immunoassay using cross-sectional and longitudinal seroconverter specimens from Africa. AIDS 21:403-8. PMID: 17301558


    Crawford, H, JG Prado, A Leslie, S Hue, I Honeyborne, S Reddy, M van der Stok, Z Mncube, C Brander, C Rousseau, JI Mullins, R Kaslow, P Goepfert, S Allen, HUNTER, E., J Mulenga, P Kiepiela, BD Walker, and PJ Goulder. (2007). Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection. J Virol 81:8346-51. PMCID: 1951305


    Brockman, MA, A Schneidewind, M Lahaie, A Schmidt, T Miura, I Desouza, F Ryvkin, CA Derdeyn, S Allen, HUNTER, E., J Mulenga, PA Goepfert, BD Walker, and TM Allen. (2007). Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A. J Virol 81:12608-182. PMCID: PMC2169025


    Rong, R, S Gnanakaran, JM Decker, F Bibollet-Ruche, J Taylor, JN Sfakianos, JL Mokili, M Muldoon, J Mulenga, S Allen, BH Hahn, GM Shaw, JL Blackwell, BT Korber, HUNTER, E., and CA Derdeyn. (2007). Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1. J Virol. 81(11):5658-68. PMCID: 1900276


    Stansel, E, R Apkarian, S Haubova, WE Diehl, EM Tytler, and HUNTER, E., (2007). Basic Residues in the Mason-Pfizer Monkey Virus Gag Matrix Domain Regulate Intracellular Trafficking and Capsid-Membrane Interactions. J Virol 81:8977-88. PMCID: 1951391


    Parker, SD, ST Rottinghaus, AJ Zajac, L Yue, HUNTER, E., RJ Whitley, and JN Parker. (2007). HIV-1(89.6) Gag expressed from a replication competent HSV-1 vector elicits persistent cellular immune responses in mice. Vaccine 25:6764-73. PMCID: 2084203


    Johnson, R. W., B. Li, S. Sunay, R. H. Moore, J. Mulenga, E. Hunter, S. Allen, J. L. Blackwell, and C. A. Derdeyn. (2006). Real-time PCR quantitation of subtype C HIV DNA in a Zambian discordant couple cohort. AIDS Res Hum Retroviruses 22:438-44. PMID: 16706621


    Ulbrich, P., S. Haubova, M. V. Nermut, E. Hunter, M. Rumlova, and T. Ruml. 2006. Distinct roles for nucleic acid in in vitro assembly of purified Mason-Pfizer monkey virus CANC proteins. J Virol 80:7089-99.


    Li, M., J. F. Salazar-Gonzalez, C. A. Derdeyn, L. Morris, C. Williamson, J. E. Robinson, J. M. Decker, Y. Li, M. G. Salazar, V. R. Polonis, K. Mlisana, S. A. Karim, K. Hong, K. M. Greene, M. Bilska, J. Zhou, S. Allen, E. Chomba, J. Mulenga, C. Vwalika, F. Gao, M. Zhang, B. T. Korber, E. Hunter, B. H. Hahn, and D. C. Montefiori. (2006). Genetic and Neutralization Properties of Acute and Early Subtype C Human Immunodeficiency Virus Type 1 Molecular env Clones from Heterosexually Acquired Infections in Southern Africa. J Virol. 80(23):11776-90. PMCID: 1642599


    Micoli, K. J., O. Mamaeva, S. C. Piller, J. L. Barker, G. Pan, E. Hunter, and J. M. McDonald. (2006). Point mutations in the C-terminus of HIV-1 gp160 reduce apoptosis and calmodulin binding without affecting viral replication. Virology 344:468-79. PMCID: 1489811


    Li, B., J. M. Decker, R. W. Johnson, F. Bibollet-Ruche, X. Wei, J. Mulenga, S. Allen, E. Hunter, B. H. Hahn, G. M. Shaw, J. L. Blackwell, and C. A. Derdeyn. (2006). Evidence for potent autologous neutralizing antibody titers and compact envelopes in early infection with subtype C human immunodeficiency virus type 1. J Virol 80:5211-8. PMCID: 1472127


    Song, C., K. Micoli, H. Bauerova, I. Pichova, and E. Hunter. (2005). Amino acid residues in the cytoplasmic domain of the Mason-Pfizer monkey virus glycoprotein critical for its incorporation into virions. J Virol 79(18):11559-68. PMCID: 1212598


    Bauerova-Zabranska, H., J. Stokrova, K. Strisovsky, E. Hunter, T. Ruml, and I. Pichova. (2005). The RNA binding G-patch domain in retroviral protease is important for infectivity and D-type morphogenesis of Mason-Pfizer monkey virus. J Biol Chem 280(51):42106-12. PMID: 16257973


    Decker, J. M., F. Bibollet-Ruche, X. Wei, S. Wang, D. N. Levy, W. Wang, E. Delaporte, M. Peeters, C. A. Derdeyn, S. Allen, E. Hunter, M. S. Saag, J. A. Hoxie, B. H. Hahn, P. D. Kwong, J. E. Robinson, and G. M. Shaw. 2005. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. J Exp Med 201:1407-19.


    Song, C., K. Micoli, and E. Hunter. (2005). Activity of the Mason-Pfizer monkey virus fusion protein is modulated by single amino acids in the cytoplasmic tail. J Virol 79(18):11569-79. PMCID: 1212599


    Burton, D. R., R. C. Desrosiers, R. W. Doms, M. B. Feinberg, R. C. Gallo, B. Hahn, J. A. Hoxie, E. Hunter, B. Korber, A. Landay, M. M. Lederman, J. Lieberman, J. M. McCune, J. P. Moore, N. Nathanson, L. Picker, D. Richman, C. Rinaldo, M. Stevenson, D. I. Watkins, S. M. Wolinksky, and J. A. Zack. 2004. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science 303:316


    Celma, C.C., J. M. Manrique, E. Hunter, J. L. Affranchino, and S. A. Gonzalez. 2004. Second-site revertants of a simian immunodeficiency virus gp41 mutant defective in envelope glycoprotein incorporation. AIDS Res Hum Retroviruses 20:733-41.


    Derdeyn, C. A., Decker, J. M., Bibollet-Ruche, F., Mokili, J. L., Muldoon, M., Denham, S. A., Heil, M. L., Kasolo, F., Musonda, R., Hahn, B. H. Shaw, G. M., Korber, B. T., Allen, S., and HUNTER, E. (2004) Envelope-constrained, neutralization-sensitive HIV-1 after heterosexual transmission. Science. 303(5666):2019-2022.


    Stansell, E., Tytler, E., Walker, M., and HUNTER, E. (2004) An early stage of Mason-Pfizer monkey virus budding is regulated by the hydrophobicity of the Gag matrix domain core. J. Virol. 78(10):5023-5031.


    Heil, M.L., J. M. Decker, J. N. Sfakianos, G. M. Shaw, E. HUNTER, and C. A. Derdeyn (2004) Baseline sensitivity of HIV-1 to the fusion inhibitors enfuvirtide and T-649 is impacted by sequences outside of the gp41 N-terminal heptad repeat. J.Virol. 78: 7582-7589.


    Song, Chisu, Dubay, Susan R., and HUNTER, E. (2003) A tyrosine motif in the cytoplasmic domain of Mason-Pfizer monkey virus is essential for the incorporation of glycoprotein into virions. J. Virol. 77(9):5192-5200.


    Lin, Xiaoxu, Derdeyn, C.A., Blumenthal, R., West, J., and HUNTER, E. (2003) Progressive truncations C-terminal to the membrane-spanning domain of SIV Env reduce fusogenicity and increase concentration dependence of Env for fusion. J. Virol. 77(12):7067-7077.


    Song, Chisu and HUNTER, E. (2003) Variable sensitivity to substitutions in the N-terminal heptad repeat of Mason-Pfizer monkey virus transmembrane protein. J. Virol. 77(14):7779-7785.


    Sfakianos, Jeffrey N. and HUNTER, E. (2003) Mason-Pfizer monkey virus capsid transport is mediated by Env/Gag interactions at the pericentriolar recycling endosome. Traffic. 4(10):671-680. (Article featured on cover.)


    Sommerfelt, M.A., Harkestad, N., and HUNTER, E. (2003) The endogenous langur type D retrovirus PO-1-Lu and its exogenous counterparts in macaque and langur monkeys. Virology. 315:275-282.


    Curlee, K.V., Hong, J.S., Claney, J.P., HUNTER, E., Berdiev, B., Benos, D., Sommerfelt, M.A., Sorscher, E.J., and Sakalian, M. (2003) Membrane transplantation corrects integral membrane protein defects. J. Mol. Med. 81:511-520.


    Manrique, J.M., Celma, C.C.P., HUNTER, E., Affranchino, J.L., and Gonzalez, S.A. (2003) Positive and negative modulation of virus infectivity and envelope glycoprotein incorporation into virions by amino acid substitutions at the N terminus of the simian immunodeficiency virus matrix protein. J. Virol. 77(20):10881-10888.


    Sfakianos, Jeffrey N., LaCasse, R.A., and HUNTER, E. (2003) The Mason-Pfizer monkey virus cytoplasmic targeting-retention signal directs nascent Gag polypeptides to a pericentriolar region of the cell. Traffic. 4(10):660-670. (Article featured on cover.)


    Sakalian, M., Dittmer, S.S., Gandy, A. D., Rapp, N.D., Zabranski, A., and HUNTER, E. (2002) The Mason-Pfizer monkey virus internal scaffold domain enables t in vitro assembly of human Immunodeficiency Virus type 1 Gag. J. Virol. 76(21):10811-10820.


    Yasuda, J., HUNTER, E., Nakao, M., and Shida, H. (2002) Functional involvement of a novel Nedd4-like ubiquitin ligase on retrovirus budding. EMBO Reports. 3(7):636-640.


    Zabransky, A., HUNTER, E., and Sakalian, M. (2002) Identification of a minimal HIV-1 Gag domain sufficient for self-association. Virology. 294:141-150.


    Ochsenbauer-Jambor, C., Delos, S.E., Accavitti, M.A., White, J.M., and HUNTER, E. (2002) Novel monoclonal antibody directed at the receptor binding site on the avian sarcoma and leukosis virus Env complex. J. Virol. 76(15):7518-7527.


    Nermut, M.V., Bron, P. Thomas, D., Rumlova, M., Ruml T., and HUNTER, E. (2002) Molecular organization of Mason-Pfizer monkey virus capsids assembled from Gag polyprotein in Escherichia coli. J. Virol. 76(9):4321-4330.


    West, J.T., Weldon, S.K., Wyss, S., Lin, X., Yu, Q., Thali, M., and HUNTER, E. (2002) Mutation of the dominant endocytosis motif in HIV-1 gp41 can complement matrix mutations without increasing Env incorporation. J. Virol. 76(7):3338-3349.


    Trask, S.A., Derdeyn, C.A., Fideli, U., Chen, Y., Meleth, S., Kasolo, F., Musonda, R., HUNTER, E., Gao, F., Allen, S., and Hahn, B.H. (2002) Molecular epidemiological of HIV-1 transmission in a heterosexual cohort of discordant couples in Zambia. J.Virol. 76(1):397-405.


    Reeves, J. D., Gallo, S. A., Ahmad, N., Miamidian, J. L., Harvey, P. E., Sharron, M., Pohlmann, S., Sfakianos, J. N., Derdeyn, C. A., Blumenthal, R., HUNTER, E., and Doms, R. W. (2002). Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proc Natl Acad Sci U S A 99(25):16249-16254.


    Celma, C.C.P., Manrique, J.M., Affranchino, J.L., HUNTER, E., and Gonzalez, S.A. (2001) Domains in the simian immunodeficiency virus gp41 cytoplasmic tail required for envelope incorporation into particles. Virology 283:253-261.


    Hong, S., Choi, G., Park, S., Chung, A-S., HUNTER, Eric, and Rhee, S.S. (2001) Type D retrovirus Gag polyprotein interacts with the cytosolic chaperonin TriC. J. Virol. 75(6):2526-2534.


    West, J.T., Johnston, P.B., Dubay, S.R., and HUNTER, E. (2001) Mutations within the putative membrane-spanning domain of the simian immunodeficiency virus transmembrane glycoprotein define the minimal requirements for fusion, incorporation, and infectivity. J. Virol. 75(20) 9601-9612.


    Derdeyn, C.A., Decker, J.M., Sfakianos, J.N., Zhang, Z., O'Brien, W.A., Ratner, L., Shaw, G.M., and HUNTER, E. (2001) Sensitivity of HIV-1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. J. Virol. 75(18) 8605-8614.


    Parker, S.D., Wall, J.S., and HUNTER, E. (2001) Analysis of Mason-Pfizer monkey virus Gag particles by scanning transmission electron microscopy. J. Virol. 75(19):9543-9548.


    Manrique, J.M., Celma, C.C.P., Affranchino, J.L., HUNTER, E., and Gonzalez, S.A. (2001) Small variations in the length of the cytoplasmic domain of the simian immunodeficiency virus transmembrane protein drastically affect envelope incorporation and virus entry. AIDS Res. Hum. Retroviruses 17(17):1615-1624.


    Guesdon, F.M.J., Greatorex, J., Rhee, S.R., Fisher, R., HUNTER, E., and Lever, A.M.L. (2001) Sequences in the 5' leader of Mason-Pfizer monkey virus which affect viral particle production and genomic RNA packaging: development of MPMV packaging cell lines. Virology 288:81-88.


    Ochsenbauer-Jambor, C., Miller, D.C., Roberts, C.R., Rhee, S.S., and HUNTER, E. (2001) Palmitoylation of the Rous Sarcoma virus TM glycoprotein is required for protein stability and virus infectivity. J. Virol. 75(23):11544-11554.


    Parker, S. D. and HUNTER, E. (2001) Activation of the Mason-Pfizer monkey virus protease within immature capsids in vitro. Proc. Natl. Acad. Sci. USA. 98(25):14631-14636


    Li, H., Haviv, Y.S., Derdeyn, C.A., Lam, J., Coolidge, C., HUNTER, E., Curiel, D.T., and Blackwell, J.L. (2001) Human immunodeficiency virus type 1-mediated syncytium formation is compatible with adenovirus replication and facilitates efficient dispersion of viral gene products and de novo-synthesized virus. Hum. Gene Ther. 12:2155-2165.


    Ochsenbauer, C., Dubay, S.R., and HUNTER, E. (2000) The Rous Sarcoma virus Env glycoprotein contains a highly conserved motif homologous to tyrosine-based endocytosis signals and displays an unusual internalization phenotype. Mol. Cell. Biol. 20(1)249-260.


    Parker, S. and HUNTER, E. (2000) A cell-line-specific defect in the intracellular transport and release of assembled retroviral capsids. J. Virol. 74(2):784-795.


    Yasuda, J. and HUNTER, E. (2000) Role of matrix protein in the type-D retrovirus replication cycle: importance of the arginine residue at position 55. Virol. 268:533-538.


    Radding, W., Williams, J.P., McKenna, M.A., Tummala, R., HUNTER, E., Tytler, E.M., and McDonald, J.M. (2000) Calmodulin and HIV type 1: interactions with Gag and Gag products. AIDS Res Hum Retroviruses. 16(15):1519-25.


    Derdeyn, Cynthia A., Decker, J.M., Sfakianos, J.N., Wu, X, O'Brien, W.A., Ratner, L., Kappes, J.C., Shaw, G.M., and HUNTER, E., (2000) Sensitivity of HIV-1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J. Virol. 74(18):8358-8367.


    Piller, Sabine C., Dubay, J.W., Derdeyn, C.A., and HUNTER, E. (2000) Mutational analysis of conserved domains within the cytoplasmic tail of gp-41 from HIV-1: Effects on glycoprotein incorporation and infectivity. J. Virol. 74(24):11717-11723.


    Rumlova-Klikova, M., HUNTER, E., Nermut, M.V., Pichova, I., and Ruml, T. (2000) Analysis of Mason-Pfizer monkey virus Gag domains required for capsid assembly in bacteria: role of the N-terminal proline residue of CA in directing the particle shape. J. Virol. 74(18), 8452-8459


    Munoz-Barrosa, I., Salzwedel, K., HUNTER, E., and Blumenthal, R. (1999) Role of the membrane proximal domain in the initial stages of HIV-1 envelope glycoprotein-mediated membrane fusion. J. Virol. 73(7):6089-6092.


    Choi, G., Park, S., Choi, B., Hong, S., Lee, J., HUNTER, E., and Rhee, S. (1999) Identification of a cytoplasmic targeting/retention signal in a retroviral Gag polyprotein. J. Virol. 73(7):5431-5437.


    Sakalian, M. and HUNTER, E. (1999) Separate assembly and transport domains within the Gag precursor of Mason-Pfizer monkey virus. J. Virol. 73(10):8073-8082.


    Rumlova-Klikova, M., Pichova, I., HUNTER, E., and Ruml, T. (1999) Conditions resulting in formation of properly assembled retroviral capsids within inclusion bodies of Escherichia coli. Collect. Czech. Chem. Commun. 64:1348-1356.


    Salzwedel, K., West, John T., and HUNTER, E. (1999) A conserved tryptophan-rich motif in the membrane-proximal region of the HIV-I gp41 ectodomain is important for Env-mediated fusion and virus infectivity. J. Virol. 73(3):2469-2480.


    Kilby, J.M., Hopkins, S., Venetta, T.M., DiMassimo, B., Cloud, G.A., Lee, J.Y., Alldredge, L., HUNTER, E., Lambert, D., Bolognesi, D., Matthews, T., Johnson, M.R., Nowak, M.A., Shaw, G.M., and Saag, M.S. (1998) Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nature Medicine. 4(11):1302-1307.


    Pichova, I., Zabransky, A., Kost'alova, I., Hruskova-Heidingsfeldova, O., Andreansky, M., HUNTER, E. and Ruml, T. (1998) Analysis of autoprocessing of Mason-Pfizer monkey virus proteinase in vitro. Three active forms of proteinase. Adv Exp Med Biol. 436:105-8.


    Zabransky, A., Andreansky, M., Hruskova-Heidingsfeldova, O., Havlicek, V., HUNTER, E., Ruml, T., and Pichova I. (1998) Three active forms of aspartic proteinase from Mason-Pfizer monkey virus. Virology. 245:250-56.


    Salzwedel, K., West, J.T., Jr., Mulligan, M.J., and HUNTER, E. (1998) Retention of the Human Immunodeficiency Virus Type 1 envelope glycoprotein in the endoplasmic reticulum does not redirect virus assembly from the plasma membrane. J. Virol. 72(9):7523-7531.


    Harrison, G.P., Miele, G., HUNTER, E., and Lever, A.M.L. (1998) Functional analysis of the core Human Immunodeficiency Virus Type 1 packaging signal in a permissive cell line. J Virol. 72(7):5886-5896.


    Yasuda, J. and HUNTER, E. (1998) A proline-rich motif (PPPY) in the Gag polyprotein of Mason-Pfizer monkey virus plays a maturation-independent role in virion release. J Virol. 72(5):4095-4103.


    Weldon, Jr., R.A., Parker, W.B., Sakalian, M., and HUNTER, E. (1998) Type D retrovirus capsid assembly and release are active events requiring ATP. J Virol. 72(4):3098-3106.


    Harrison, G.P., Mayo, M.S., HUNTER, E., and Lever, A.M.L. (1998) Pausing of reverse transcriptase on retroviral RNA templates is influenced by secondary structures both 5' and 3 of the catalytic site. Nucleic Acids Research. 26(14):3433-3442.


    Wu, X., Liu, H., Xiao, H., Conway, J.A., HUNTER, E., and Kappes, J.C. (1997) Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein. EMBO Journal 16(16):5113-22.


    Einfeld, D.A. and HUNTER, E. (1997) Mutational analysis of the oligomer assembly domain in the transmembrane subunit of the Rous sarcoma virus glycoprotein. J Virol. 71(3):2383-2389.


    Conte, M.R., Klikova, M., HUNTER, E., Ruml, T. and Matthews S. (1997) The three-dimensional solution structure of the matrix protein from the type D retrovirus, the Mason-Pfizer monkey virus, and implications for the morphology of retroviral assembly. EMBO J. 16(19):5819-26.


    Pan, Z., Radding, W., Zhou, T., HUNTER, E., Mountz, J., McDonald, J.M. (1996) Role of calmodulin in HIV-potentiated Fas-mediated apoptosis. Amer. J. Path. 149(3):903-10.


    Radding, W., Pan, A.Q., HUNTER, E., Johnston, P., Williams, J.P., and McDonald, J. (1996) Expression of the HIV-1 envelope glycoprotein alters cellular calmodulin. Biochem. Biophys. Res. Comm. 218(1):192-197.


    Sakalian, M., Parker, S.D., Weldon Jr., R.A., and HUNTER, E. (1996) Synthesis and assembly of retrovirus precursors into immature capsids in vitro. J. Virol. 70(6):3706-3715.


    HUNTER, E. (1996) Perspective: Research highlights at the University of Alabama at Birmingham Center for AIDS Research. Paradigm shifts, translational research and CFARs. AIDS Res Hum Retro 12(14):1301-1303.


    Hruskova-Heidingsfeldova, O., Andreansky, M., Fabry, M., Blaha, I., Strop, P., and HUNTER, E. (1995) Cloning, bacterial expression and characterization of the Mason -Pfizer Monkey Virus proteinase. J. Biol. Chem. 270(25):15053-15058.


    Dubay, J.W., Roberts, S.J., Shin, H-J., and HUNTER, E. (1995) Analysis of the cleavage site of the Human Immunodeficiency Virus Type 1 glycoprotein: Requirement of cleavage for glycoprotein incorporation. J. Virol. 69(8):4675-4682.


    Harrison, G.P., HUNTER, E., and Lever, A.M.L. (1995) Secondary structure model of the Mason-Pfizer Monkey Virus 5' leader sequence: Identification of a structural motif common to a variety of retroviruses. J. Virol. 69(4):2175-2186.


    Johnston, P., Dong, J.-Y., and HUNTER, E. (1995) Transport of a lysosomally-targetted Rous sarcoma virus envelope glycoprotein involves transient expression on the cell surface. Virology 206(1):353-361.


    Klikova, M., Rhee, S.S., HUNTER, E., and Ruml, T. (1995) Efficient in vivo and in vitro assembly of retroviral capsids from precursor proteins expressed in bacteria. J. Virol. 69(2):1093-1098.


    Wild, C., Dubay, J.W., Greenwell, T., Baird Jr., T., Oas, T., McDanal, C., HUNTER, E., and Matthews, T. (1994) The propensity for a leucine zipper-like domain of HIV-1 gp41 to form oligomers correlates with a role in virus-induced fusion rather than assembly of the glycoprotein complex. Proc. Natl. Acac. Sci. 91(26):12676-12680.


    Bernstein, H.B., Tucker, S.P., Kar, S.R., McPherson, S.A., McPherson, D.T., Dubay, J.W., Lebowitz, J., Compans, R.W., and HUNTER, E. (1994) Oligomerization of the hydrophobic HEPTAD repeat of gp41. J. Virol. 69(5):2745-2750.


    Andreansky, M. and HUNTER, E. (1994) Phagemid pSIT permits efficient in vitro mutagenesis and tightly controlled expression in E. coli. Biotechniques 16(4):626-633.


    Brody, B.A., Kimball, M.G., and HUNTER, E. (1994) Mutations within the transmembrane glycoprotein of Mason-Pfizer Monkey virus: Loss of SU-TM association and effects on infectivity. Virology 202(2):673-683.


    Einfeld, D.A. and HUNTER, E. (1994) Expression of the TM protein of Rous sarcoma virus in the absence of SU shows that this domain is capable of oligomerization and intracellular transport. J. Virol. 68(4):2513-2520.


    Brody, B.A., Rhee, S.S., and HUNTER, E. (1994) Postassembly cleavage of a retroviral glycoprotein cytoplasmic domain removes a necessary incorporation signal and activates fusion activity. J. Virol. 68(7):4620-4627.


    Bernstein, H.B., Tucker, S.P., HUNTER, E., Schutzbach, J.S., and Compans, R.W. (1994) Human Immunodeficiency Virus Type 1 envelope glycoprotein is modified by O-linked oligosaccharides. J. Virol. 68(1):463-468.


    Bray, M., Prasad, S., Dubay, J.W., HUNTER, E., Jeang, K-T., Rekosh, D. and Hammarskjold, M-L. (1994) A small element from the Mason-Pfizer Monkey virus genome makes HIV-1 expression and replication rev-independent. Proc. Nat. Acad. Sci. USA 91:1256-1260.


    Peng, S., Sommerfelt, M.A., Logan, J., Huang, Z., Jilling, T., Kirk, K., HUNTER, E. and Sorscher, E. (1993) One step affinity isolation of recombinant protein using the baculovirus/insect cell expression system. Protein Expression and Purification. 4:95-100.


    Salzwedel, K., Johnston, P.B., Roberts, S.J., Dubay, J.W., and HUNTER, E. (1993) Expression and characterization of glycophospholipid-anchored Human Immunodeficiency Virus Type 1 envelope glycoproteins. J. Virol. 67(9):5279-5288.


    Johnston, P.B., Dubay, J.W., and HUNTER, E. (1993) Truncations of SIV transmembrane protein confer expanded virus host range by removing a block to virus entry into cells. J. Virol. 67(6):3077-3086.


    Dong, J., and HUNTER, E. (1993) Analysis of retroviral assembly using a vaccinia/T7-polymerase complementation system. Virology 194:192-199.


    Peng, S., Sommerfelt, M.A., Berta, G., Berry, A.K., Kirk, K.L., HUNTER, E., and Sorscher, E.J. (1993) Rapid purification of recombinant baculovirus using fluorescence activated cell sorting. Biotechniques. 14(2):274-277.


    Sommerfelt, M.A., Roberts, C.R., and HUNTER, E. (1993) Expression of Simian Type D retroviral (Mason-Pfizer Monkey Virus) capsids in insect cells using recombinant Baculovirus. Virology 192:298-306.


    Dong, J., Roth, M.G., and HUNTER, E. (1992) A chimeric avian retrovirus containing the influenza hemagglutinin gene has an expanded host range. J. Virol. 66(12):7374-82.


    Strambio de Castillia, C., and HUNTER, E. (1992) Mutational analysis of the major homology region of Mason-Pfizer Monkey Virus by use of saturation mutagenesis. J. Virol. 66(12): 7021-32.


    Dubay, J.W., Roberts, S.J., Hahn, B.H., and HUNTER, E. (1992) Truncation of the HIV-1 transmembrane glycoprotein cytoplasmic domain blocks virus infectivity. J. Virol. 66(11):6616-6625.


    Sommerfelt, M.A., Rhee, S.S., and HUNTER, E. (1992) Importance of p12 protein in Mason-Pfizer monkey virus assembly and infectivity. J. Virol. 66(12):7005-7011.


    Vile, R.G., Ali, M., HUNTER, E., and McClure, M.O. (1992) Identification of a generalised packaging sequence for D-type retroviruses and generation of a D-type retroviral vector. Virology 189:786-791.


    Gallaher, W.R., Segrest, J.P., and HUNTER, E. (1992) Are fusion peptides really "sided" insertional helices? Letter to the Editor. Cell 70:531-532.


    Dubay, J.W., Roberts, S.J., Brody, B. and HUNTER, E. (1992) Mutations in the Leucine Zipper region of the Human Immunodeficiency Virus Type 1 transmembrane glycoprotein affect fusion and infectivity. J. Virol. 66(8): 4748-4756.


    Dong, J.Y., Dubay, J, Perez, L. and HUNTER, E. (1992) Mutations within the proteolytic cleavage site of the Rous Sarcoma Virus glycoprotein define a requirement for dibasic residues for intracellular cleavage. J. Virol. 66:865-874.


    Elder, J.H., Lerner, D.L., Hasselkus-Light, C.S., Fontenot, D.J., HUNTER, E., Luciw, P.A., Montelaro, R.C., and Phillips, T.R. (1992) Distinct subsets of retroviruses encode dUPTase. J. Virol. 66(3):1791-1794.


    Ivanoff, L., Morris, J.F., Gutshall, L., Sternberg, E.J., Matthews, T.J., Petteway, S.R., Dubay, J., Roberts, S.J., and HUNTER, E. (1992) The V3 loop region of the HIV-1 gp120 envelope protein is essential for virus infectivity. Virology 187: 423-432.


    McPherson, D.T., Morrow, C., Minehan, D., Wu, J., HUNTER, E., and Urry, D.W. (1992) Production and purification of a recombinant elastomeric polypeptide, G-(VPGVG)19-VPGV from E. coli. Biotechnology Progress. 8:347-352.


    Brody, B.A. and HUNTER, E. (1992) Mutations within the env gene of MPMV: Effects on protein transport and SU/TM association. J Virol. 66(6):3466-3475.


    Brody, B.A., Rhee, S.S., Sommerfelt, M.A., and HUNTER, E. (1992) A viral protease-mediated cleavage of the transmembrane glycoprotein of Mason Pfizer monkey virus can be suppressed by mutations within the matrix protein. Proc. Natl. Acad. Sci. USA. 89:3443-3447.


    Brody, B.A., HUNTER, E., Lasarow, R., Kluge, J.D., Gardner, M. and Marx, P. (1992) Protection of macaques against infection with Simian Type D Retrovirus (SRV-1) by immunization with recombinant vaccinia virus expressing the envelope glycoproteins of either SRV-1 or Mason Pfizer Monkey Virus (SRV-3). J Virol. 66(6):3950-3954.


    Sommerfelt, M.A., Petteway Jr., S.R., Dreyer, G. and HUNTER, E. (1992) Effect of retroviral proteinase inhibitors on MPMV maturation and TM glycoprotein cleavage. J. Virol. 66(7):4220-27.


    Dubay J.W., Shin, H.-J., Dong, J.-Y., Roberts, S. and HUNTER, E. (1991) Structure-function analysis of the HIV glycoprotein. Adv. Exp. Med. Biol. 303:39-46.


    Owens, R.J., Dubay, J.W., HUNTER, E., and Compans, R.W. (1991) Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells. Proc. Natl. Acad. Sci. USA 88:3987-3991.


    Rhee, S.S. and HUNTER, E. (1991) Amino acid substitutions within the matrix protein of type D retroviruses affect assembly, transport, and membrane association of a capsid. The EMBO J. 10(3):535-546.


    Desrosiers, R.C. and HUNTER, E. (1991) AIDS Biosafety. Letter to the Editor, Science 252:1231.


    Bennett, R.P., Rhee, S., Craven, R.C., HUNTER, E., and Wills, J.W. (1991) Amino acids encoded downstream of are not required by Rous Sarcoma virus protease during Gag-mediated assembly. J. Virol. 65(1):272-280.


    Rhee, S., Hui, H. and HUNTER, E. (1990) Preassembled capsids of D-type retroviruses contain a signal sufficient for targeting specifically to the plasma membrane. J. Virol. 64(8):3844-3852.


    Rhee, S. and HUNTER, E. (1990) Structural role of the matrix protein of D-type retroviruses in -polyprotein stability and capsid assembly. J. Virol. 64(9)):4383-4389.


    Rhee, S. and HUNTER, E. (1990) A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus. Cell. 63:77-86.


    Hearing, J., HUNTER, E., Rodgers, L., Gething, M-J. and Sambrook, J. (1989). Isolation of Chinese hamster ovary cell lines temperature-conditional for the cell-surface expression of integral membrane glycoproteins. J. Cell Biol. 108:339-353.


    Einfeld, D. and HUNTER, E. (1988). Oligomeric structure of a prototype retrovirus glycoprotein. Proc. Natl. Acad. Sci. USA. 85:8688-8692.


    Chatterjee, S. and HUNTER, E. (1987). Recombinant human interferons inhibit replication of Mason-Pfizer monkey virus in primate cells. Virology 157:548-551.


    Davis, G.L. and HUNTER, E. (1987). A charged amino acid substitution within the transmembrane domain of the Rous sarcoma virus envelope glycoprotein affects surface expression but not intracellular transport. J. Cell Biol. 105:1191-1203.


    Perez, L., Wills, J. W. and HUNTER, E. (1987). Expression of the Rous sarcoma virus env gene from a simian virus 40 late-region replacement vector: Effects of upstream initiation codons. J. Virol. 61:1276-1281.


    Thielan, B. J, HUNTER, E., Desrosiers, R. C. and Ratner, L. (1987) Trans-activation of long terminal repeat sequence-mediated gene expression is not a property of type D retrovirus replication. J. Gen. Virol. 2265-2270.


    Rhee, S. S. and HUNTER, E. (1987). Myristylation is required for intracellular transport but not for assembly of D-type retrovirus capsids. J. Virol. 61:1045-1053.


    Perez, L. and HUNTER, E. (1987). Mutations within the proteolytic cleavage site of the Rous sarcoma virus glycoprotein precursor block processing to gp85 and gp37. J. Virol. 61:1609-1614.


    Perez, L., Davis, G. L. and HUNTER, E. (1987). Mutants of the Rous Sarcoma Virus envelope glycoprotein that lack the transmembrane anchor and/or cytoplasmic domains: Analysis of Intracellular transport and assembly into virions. J. Virol. 61:2981-2988.


    Sonigo, P., Barker, C., HUNTER, E. and Wain-Hobson, S. (1986). Nucleotide sequence of Mason-Pfizer Monkey virus: An Immunosuppressive D-type retrovirus. Cell 45:375-385.


    Bryant, M., Gardner, M., Marx, P., Maul, D., Lerche, N., Osborn, K., Lowenstine, L., Bogden, A., Arthur, L. and HUNTER, E. (1986). Immunodeficiency in rhesus monkeys associated with the original Mason-Pfizer monkey virus. J. Natl. Cancer Inst., 77:957-965.


    Lerche, N. W., Osborn, K. G., Marx, P. A., Prahalada, S., Maul, D. H., Lowenstine, L. J., Munn, R. J., Bryant, M. L., Henrickson, R. V., Arthur, L. O., Gilden, R. V., Barker, C. S., HUNTER, E. and Gardner, M. B. (1986). Inapparent carriers of simian aids type D retrovirus and disease transmission with saliva. J. Natl. Cancer Inst. 77:489-496.


    Barker, C. S., Pickel, M., Tainsky, M. and HUNTER, E. (1986). Molecular cloning of the Mason-Pfizer monkey virus genome: Cloning of integrated and unintegrated proviral DNAs and a molecular comparison and B, C and D type retroviruses. Virology 153:201-214.


    Hardwick, J. M., Shaw, K., Wills, J. W., and HUNTER, E. (1986). Amino-terminal deletion mutants of the Rous sarcoma virus glycoprotein do not block signal peptide cleavage, but can block exocytosis. J. Cell Biology 103:829-838.


    Bradac, J., and HUNTER, E. (1986). Polypeptides of Mason-Pfizer Monkey virus. III. Translational order of proteins on the and env gene specified precursor polypeptides. Virology 150:503-508.


    Bradac, J., Chatterjee, S., and HUNTER, E. (1986). Polypeptides of Mason-Pfizer monkey virus. II. Synthesis and Processing of the env gene products. Virology 150:491-502.


    Chatterjee, S., Bradac, J., and HUNTER, E. (1985). A rapid screen ing procedure for the isolation of nonconditional replicatin mutans of Mason-Pfizzer monkey virus: Identification of a mutant defect in pol. Virology 141:65-76


    Marx, P. A., Osborn, K. G., Maul, D. H., Lerche, N. W., Henrickson, R. V. Shiigi, S. M., Wilson, B. J., Malley, A., Olson, L. C., Arthur, L. O., Gilden, R. V., Barker, C. S., HUNTER, E., Munn, R. J., Bryant, M. L., Heidecker, G., Gardner, M. (1985). Isolation of a new strain of SAIDS type-D retroviruses from Celebes Black Macaques (Macaca Nigra) with immune deficiency and retroperitoneal fibromatotosis. J. Virol. 56:571-578.


    Chatterjee, S., HUNTER, E, and Whitley, R. (1985). Effect of cloned human interferons on protein synthesis and morphogenesis of Herpes Simplex virus. J. Virol. 56:419-425.


    Barker, C., Wills, J., Bradac, J., and HUNTER, E. (1985). Molecular cloning of the Mason-Pfizer monkey virus genome: Characterization and cloning of subgenomic fragments. Virology 142:223-240.


    Desrosiers, R. C., Daniel, M. D., Butler, C. V., Schmidt, D. K., Letvin, N. L., Hunt, R. D., King, N. W., Barker, C. S., HUNTER, E. (1985). Retrovirus D/New England and Its Relation to Mason-Pfizer Monkey virus. J. Virol. 54:552-560.


    Chatterjee, S., Lakeman, A. D., Whitley, R. J., and HUNTER, E. (1984). Effect of cloned and human interferons on the replication of an cell fusion induced by Herpes Simplex virus. Virus Res. 1:81-87.


    Bradac, J., Chatterjee, S., and HUNTER, E. (1984). Polypeptides of Mason-Pfizer Monkey virus: I. Synthesis and processing of the gene products. Virology 138:260-275.


    Wills, J. W., Srinivas, R. V., and HUNTER, E. (1984). Mutations of the Rous sarcoma virus env gene that affects the transport and subcellular localization of the glycoprotein products. J. Cell Biol. 99:2011-2023.


    Bhown, A. S., Bennett, J. C., Cornelius, T. W., and HUNTER, E. (1983). Exclusive use of high pressure liquid chromatography for the determination of the complete amino acid sequence of the 12K fragment of avian sarcoma virus structural protein p27. J. Liq. Chrom. 6(2):249-258.


    HUNTER, E., Bennett, J. C., Bhown, A., Pepinsky, R. B., and Vogt, V. M. (1983). Amino terminal amino acid sequence of p10, the fifth polypeptide of avian sarcoma and leukemia viruses. J. Virol. 45:885-888.


    HUNTER, E., Hill, E., Hardwick, M., Bhown, A., Schwartz, D., and Tizard, R. (1983). Complete Sequence of the Rous Sarcoma virus env gene: Identification of structural and functional regions of its product. J. Virol. 46:920-936.


    Wills, J. W., Hardwick, J. M., Shaw, K., and HUNTER, E. (1983). Alterations in the transport and processing of RSV envelope glycoproteins mutated in the signal and anchor regions. J. Cell Biochem. 23:81-94.


    Chatterjee, S., Bradac, J., and HUNTER, E. (1982). Effect of monensin on Mason-Pfizer Monkey virus glycoprotein synthesis. J. Virol. 44:1003-1012.


    Chatterjee, S., Cheung, H. C., and HUNTER, E. (1982). Interferon inhibits Sendai virus-induced cell fusion - an effect on cell membrane fluidity. Proc. Natl. Acad. Sci. USA 79:835-839.


    Chatterjee, S., Bradac, J., and HUNTER, E. (1981). Effect of tunicamycin on cell fusion induced by Mason-Pfizer monkey virus. J. Virol. 38:770.


    Bhown, A. S., Bennett, J. C., Mole, J. E., and HUNTER, E. (1981). Purification and characterization of the gene products of avian type C-retroviruses by high pressure liquid chromatography. Anal. Biochem. 112:128.


    Hardwick, J. M., and HUNTER, E. (1981). Rous sarcoma virus mutant LA3382 is defective in virion glycoprotein assembly. J. Virol. 40:752-761.


    Bhown, A. S., Bennett, J. C., and HUNTER, E. (1980). Alignment of the peptides derived from acid catalysed cleavage of an aspartylprolyl bond in the major internal structural polypeptide of avian retroviruses. J. Biol. Chem. 255:6965


    Chatterjee, S., and HUNTER, E. (1980). Inhibition of Mason-Pfizer monkey virus-induced syncytium formation in normal human cells by homologous interferon. Virology. 104:487-490.


    Chatterjee, S., and HUNTER, E. (1980). Fusion of normal primate cells: A common biological property of the 'D' type retroviruses. Virology 107:100-108.


    Vogt, P. K., Hayman, M., HUNTER, E., and Duesberg, P. H. (1979). A non-conditional replication-defective mutant of the Schmidt-Ruppin strain of Rous Sarcoma virus. Virology 95:421-433.


    Barbacid, M., HUNTER, E., and Aaronson, S. A. (1979). Avian reticuloendotheliosis viruses: Evolutionary linkage with mammalian type C retroviruses. J. Virol. 30:508-514.


    Stohrer, R., and HUNTER, E.(1979). Inhibition of Rous Sarcoma virus replication by 2-deoxyglucose and tunicamycin: Identification of an unglycosylated env gene product. J. Virol. 32:412-419.


    Chatterjee, S., and HUNTER, E. (1979). The characterization of Mason-Pfizer monkey virus-induced cell fusion. Virology 95:421-433.


    Miller, G. G., Blair, D. G., HUNTER, E., Mousa, G. Y., and Trevithick, J. R. (1979). Differentiation of rat lens epithelial cells in tissue culture (III) functions in vitro of a transformed rat lens epithelial cell line. Develop., Growth and Differ., 21:19-27.


    HUNTER, E., Bhown, A. S., and Bennett, J. C. (1978). Amino-terminal amino acid sequence of the major structural polypeptides of avian retroviruses: Sequence homology between reticuloendotheliosis virus p30 and p30s of mammalian retroviruses. Proc. Natl. Acad. Sci. USA 75:2708-2712.


    Bister, K., Varmus, H. E., Stavnezer, E., HUNTER, E., and Vogt, P. K. (1977). Biological and biochemistry studies on the inactivation of avian oncoviruses by ultraviolet irradiation. Virology 77:689-707.


    HUNTER, E. and Vogt. P. K. (1976). Temperature-sensitive mutants of avian sarcoma Genetic recombination with wild type sarcoma virus and physiological analyses of multiple mutants. Virology 69:23-24.


    Blair, D. G., Mason, W. S., HUNTER, E., and Vogt, P. K. (1976). Temperature-sensitive mutants of avian sarcoma viruses: Genetic recombination between multiple or coordinate mutants and avian leukemia viruses. Virology 75:48.


    HUNTER, E., Hayman, M. J., Rongey, R. W., and Vogt, P. K. (1976). An avian sarcoma virus mutant that is temperature sensitive for virion assembly. Virology 69:35.


    Verma, I., and HUNTER, E. (1976). Reverse transcriptase is coded for by the viral RNA. Comparative Biochemistry, Molecular Biology, and Immunology of RNA Tumor Virus. Bibliotheca Haematologica 43:457.


    Hayman, M. J., HUNTER, E., and Vogt, P. K. (1976). Inhibition of avian sarcoma virus replication by glucosamine: A specific effect on the synthesis and processing of viral proteins. Virology 71:402.


    Verma, I., Varmus, H. E., and HUNTER, E. (1976). Characterization of "Early" Temperature-Sensitive mutants of avian sarcoma viruses: Biological properties, thermolability of reverse transcriptase in vitro and synthesis of viral DNA. Virology 74:16.


    HUNTER, E., Friis, R. R., and Vogt, P. K. (1974). Inhibition of avian sarcoma virus replication by glucosamine. Virology 58:499-450.


    Friis, R. R. and HUNTER, E. (1973). A temperature sensitive mutant of Rous sarcoma virus that is defective for replication. Virology 53:479-483


    Negroni, G. and HUNTER, E. (1973). Rejection of polyoma virus-induced neoplasms in mice inoculated with complement and antiserum. J. Natl. Cancer Inst. 51:265-268.


    HUNTER, E. and Negroni, G. (1972). Isolation in newborn mice of tumor cell variants from a polyoma-transformed non-malignant cell line. Europ. J. Cancer 8:107-109.


    Negroni, G. and HUNTER, E. (1971). Antigenic heterogeneity in cell populations of cloned polyoma virus induced tumor lines. Nature New Biol. 230:18-20.


    Book Chapters -

    HUNTER, E. (2001) Virus Assembly. In: Fields Virology, Fourth Edition. Eds. D.M. Knipe and P.M. Howley. Lippincott, Williams & Wilkins, Philadelphia, PA, Vol. 1, Chap. 8:171-197.


    HUNTER, E., Casey, J., Hahn, B., Hayami, M., Korber, B., Kurth, R., Neil, J., Rethwilm, A., Sonigo, P. and Stoye, J. (2000). Retroviridae. In: Virus Taxonomy. Seventh Report of the International Committee on Taxonomy of Viruses. Eds. van Regenmortel, M.H.V., et al., London, San Diego: Academic Press, pp 369-387.