Pathology Faculty Member

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  • Contact Information:

    Emory University Hospital, Room F-149A
    1364 Clifton Rd NE
    Atlanta, GA 30322
    404 712-7911 Phone

    For an expert Pathology consultation,
    or to send a specimen, call:

    1-404-712-5947


    Alexis B Carter, MD

    Pathology Informatics

    Assistant Professor
    Pathology & Laboratory Medicine


    Pathology Faculty Photo

    Other Appointments/Positions

    Member, Center for Comprehensive Informatics

    Director of Pathology Informatics, Emory University School of Medicine


    Pathology Division(s):
    Clinical Pathology


    Email Address:
    abcart2@emory.edu


    Education:

    BS   University of Georgia, 1990 - 1994

    MD   Medical College of Georgia, 1994 - 1998

    AP/CP Residency   East Carolina University, 1998 - 2003

    Molecular Genetic Pathology Fellowship   University of Pittsburgh Medical Center, 2003 - 2004

    Research in Mol. Path. & Informatics   University of Pittsburgh Medical Center, 2004 - 2005



    Research Interests:

    - Software Development for Laboratories
    Laboratories benefit from small software programs that fill gaps in functionality left vacant by Laboratory Information Systems (LIS). These small and easy-to-code programs increase efficiency, decrease turnaround time and improve the quality of patient care by performing complex calculations, automated quality control checking, error flagging and unique functionality specific to discrete pathology subspecialties. Current Projects: - Lightweight and portable Bone Marrow and Blood Counter - Rapid Desktop Image Capture and Storage for Inexpensive Telepathology Systems


    - Web Application Development for Laboratories
    The use of the Internet and Wide-Area Networks have revolutionized the field of medicine. The specialized nature of Pathology and its subspecialties make the Internet the ideal venue by which clinical services can be delivered. This includes telepathologic diagnosis on specimens required at remote sites as well as electronic order entry and result display to and from outreach facilities. Efforts to begin telepathology services are currently being investigated.


    - Telepathology
    My work is focused on the intelligent, practical and compliant use of digital imaging systems for pathology practice in patient care.


    - Transfusion utilization and information systems
    I am involved in several projects which look at how information systems can improve transfusion practice, both from a clinical as well as laboratory perspective.


    - Laboratory Information Systems for Molecular Diagnostic Testing
    Few systems exist that meet the data storage needs of specialized laboratories which perform molecular tests. This is primarily because of the relative newness of the field and the high complexity of the testing. I am developing systems that meet these needs in both the clinical and research arenas in an open-source format.


    - Molecular testing on paraffin-embedded tissues.
    Tissues which have been fixed and subsequently embedded in paraffin constitute the vast majority of solid tissues stored in the pathology laboratory. Unfortunately, these tissues are not the best specimens for molecular techniques. Degradation of genetic material, difficult-to-remove inhibitors and fixatives containing chemicals which prevent the polymerase chain reaction all contribute to difficulty or inability to use these tissues for diagnosis. Dr. Carter is interested in discovering new ways to extract genetic material that will improve the ability to perform testing on these pervasive specimens as well as to test current molecular techniques against newer, less toxic fixatives.



    Clinical Focus:

    As Director of Pathology Informatics, I coordinate projects and translate functional needs related to our various laboratory information systems at the faculty level between the Departments of Pathology and Information Services. My clinical responsibilities also include interpretation of high-complexity tests in molecular hematopathology.


    Honors / Awards:

    Poster Award, Laboratory Information Systems and Medical Informatics (LISMI) Division, Annual Meeting of the American Association of Clinical Chemistry (AACC) in Anaheim, California, USA, July 2010 for abstract entitled Patient Misidentifications Caused by Errors in Standard Barcode Technology, 2010

    Best Scientific Session in Pathology Informatics, October 2008. Advancing Practice, Instruction and Innovation through Informatics, Pittsburgh, PA., 2008

    Specialty Boards:

    2003 Clinical Pathology American Board of Pathology


    2003 Anatomic Pathology American Board of Pathology


    2005 Molecular Genetic Pathology American Board of Pathology


    Selected Publications:

    Published and Accepted Research Articles -

    Snyder ML, Carter AB, Jenkins K, Fantz CR. Patient Misidentifications Caused By Errors in Standard Barcode Technology. Clin Chem. Aug 11 2010. CLICK HERE FOR PUBMED LINK.


    Williams S, Henricks WH, Becich MJ, Toscano M, Carter AB. Telepathology for patient care: what am I getting myself into? Adv Anat Pathol. Mar 2010;17(2):130-149. CLICK HERE FOR PUBMED LINK.


    Carter AB, Howanitz PJ. Intraoperative testing for Parathyroid Hormone (PTH): A Comprehensive Review of the Use of the Assay and the Relevant Literature. Arch Pathol Lab Med. 2003;127(11):1424-1442. CLICK HERE FOR PUBMED LINK.


    Hortin GL, Carter AB. Intraoperative Parathyroid Hormone Testing: Survey of Testing Program Characteristics. Arch Pathol Lab Med. 2002;126(9):1045-1049. CLICK HERE FOR PUBMED LINK.


    Dobbs LJ, Madigan MN, Carter AB, Earls L. Use of FTA gene guard filter paper for the storage and transportation of tumor cells for molecular testing. Arch Pathol Lab Med. 2002;126(1):56-63. CLICK HERE FOR PUBMED LINK.


    Carter AB, Price DL, Tucci KA, Lewis GK, Mewborne J, Singh HK. Choroid plexus carcinoma presenting as an intraparenchymal mass: A case report. J Neurosurg. 2001;95(6):1040-1044. CLICK HERE FOR PUBMED LINK.


    Byrne AL*, Camann MA, Cyr TL, Catts EP, Espelie KE. Forensic implications of biochemical differences among geographic populations of the black blow fly, Phormia regina (Meigen). J Forensic Sci. 1995;40:372-377. *Published under maiden name (Alexis L. Byrne). CLICK HERE FOR PUBMED LINK.


    Other Publications -

    Carter AB, Aller R, 2010, HIMSS10: Pathologist Perspectives from the Newcomer and the Seasoned Attendee: Pathologists should attend!, J Pathol Inform, 1, 6


    Williams SM, Khire S, Jayant N, Carter AB, Srinath U, 2010, One-Stage and Two-Stage Models for Compressing Pathology Slides, Arch Pathol Lab Med, 134(6), 942 (Presented at Advancing Practice, Instruction and Innovation through Informatics Annual Meeting (Pittsburgh, Pennsylvania, USA) on September 21, 2009)


    Snyder ML, Carter AB, Fantz CR, 2010, Patient Misidentifications Caused By Errors in Standard Barcode Technology, Poster presentation at the American Association for Clinical Chemistry Annual Meeting (Anaheim, California, USA), July 27, 2010


    Carter AB, Williams SM, Jayant N, 2009, Diagnostically Lossless Compression of Pathology Image Slides [abstract], Arch Pathol Lab Med, 133, 1150 (Presented at Advancing Practice, Instruction and Innovation through Informatics Annual Meeting (Pittsburgh, Pennsylvania, USA) on October 20, 2008)


    SJ Sirintrapun, MJ Schniederjan, S Logani, AB Carter, 2009, Validation of an Inexpensive Telepathology System for Frozen Section Diagnosis, Mod Pathol, 22(1s), 300A


    Carter AB, Schniederjan S, Mann KE, 2009, Software for the Laboratory: the Blood and Bone Marrow Counter [abstract], Arch Pathol Lab Med, 133, 1150 (Presented at Advancing Practice, Instruction and Innovation through Informatics Annual Meeting (Pittsburgh, Pennsylvania, USA) on October 20, 2008)


    Gullapalli RR, Carter AB, Kant JA, 2008, Automated Data Analysis of Real-Time PCR Data Using a Modular Programming Approach [Abstract], J Mol Diagn, 10(6), 613 (Poster presentation at the Association for Molecular Pathology Annual Meeting in Grapevine, Texas, USA; November 2008)


    Carter AB. Information Systems for MDx Laboratories, Part 2. Advance for Administrators of the Laboratory. 2008;17(1):16-18.


    Carter AB. Information Systems for MDx Labs, Part 1. Advance for Administrators of the Laboratory. 2007;16(11):18-20.


    Carter AB, Melan MA, Sheikh H, Kant JA, 2007, Extraction of DNA from Formalin-Fixed Paraffin-Embedded Tissues: A Comparison of Methods [abstract], J Mol Diagn, 9(5), 702 (Poster presentation at the Association for Molecular Pathology Annual Meeting in Los Angeles, CA; November 7-10, 2007)


    Carter AB, Busch RP, Kant JA, and Harrison JH, 2006, Simple Programming for the Molecular Diagnostics Laboratory: Automated Data Analysis for Increased Accuracy and Efficiency [abstract], Arch Pathol Lab Med, 130(6), 892


    Carter AB, Harrison JH, Kant JA, 2006, Database Design for a Molecular Pathology Laboratory [abstract], Presented at the 40th annual meeting of the Academy of Clinical Laboratory Physicians and Scientists (ACLPS) (Pittsburgh, Pennsylvania, USA) on June 10, 2005


    Melan M, Carter AB and Kant JA, 2004, Assessment of t(9;22) BCR-ABL Transcript Levels Using Relative Quantification Levels [abstract], J Mol Diag, 6(4), 415


    Carter AB, Uhrmacher J, Baysal BE, Li KC, Monzon-Bordonaba FA, and Kant JA, 2004, Clinical Testing for Hereditary Paraganglioma [abstract], Annual meeting of the Association for Molecular Pathology (Los Angeles, CA) and American Society of Human Genetics (Toronto, Canada), published online through the American Society of Human Genetics website


    Carter AB and Catrou PG, 2002, The Online Evaluation System (OES): An Intranet-Based Method of Submitting, Tabulating and Reporting Departmental Evaluations [abstract], Arch Pathol Lab Med, 126(7), 798


    Carter AB and Dobbs LJ, 2002, Web-Based Continuing Medical Education (WBCME): Evaluating Need in North Carolina [abstract], Arch Pathol Lab Med, 126(7), 801


    Carter AB, Christie JD, Kragel PK, 2002, Primary Amebic Meningoencephalitis, ASCP Check Sample: Surgical Pathology II, 26, 43-64


    Carter AB, Halliday BE, 2000, Choroid plexus carcinoma, ASCP Check Sample: Surgical Pathology I, 28(3), 37-54


    Madigan MN, Carter AB and Dobbs LJ, 2000, Use of the FTA® System for the Storage and Transportation of Lymphoma Cells for Molecular Testing [abstract], J Mol Diag, 2, 228