Pathology Faculty Member

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    Anatomic Pathology
    First Floor EUH Rm H-187
    Atlanta GA
    404-712-8851 Phone

    For an expert Pathology consultation,
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    Krisztina Z Hanley, MD

    Cytopathology, Gynecologic and Breast Pathology

    Associate Professor
    Pathology & Laboratory Medicine

    Pathology Faculty Photo

    Other Appointments/Positions

    Associate Professor, Emory Clinic

    Rotation Director, Gynecologic Pathology, Department of Pathology at Emory University Hospital

    Medical Director of Macroscopy and Gross Rooms, Emory University Hospital and Emory University Hospital at Midtown

    Assitant Program Director Pathology Residency Program, Pathology and Laboratory Medicine

    Pathology Division(s):
    Anatomic Pathology

    Email Address:


    Medical Doctor   University of Pecs, Medical and Health Sciences Centre, Pecs, Hungary, 1995 - 2001

    AP/CP residency   University of Rochester Medical Center, Rochester, NY, 2003 - 2007

    Cytopathology Fellow   Emory University School of Medicine, Atlanta, GA, 2007 - 2008

    Gynecologic Pathology Fellow   University of Virginia, Charlottesville, VA, 2008 - 2009

    Research Interests:

    My primary research focus is on clinicopathologic study of gynecologic malignancies in young women. In addition I`m involved in the ongoing GOG studies within the Emory Health System and a smaller projects related to the role of HPV in cervical carcinogenesis.

    Clinical Focus:

    My primary clinical contribution is divided between surgical pathology (gynecologic and breast service) and cytopathology. About 60% of my professional time is dedicated to these two clinical services. Additional contributions to clinical services include: ¿ Expended the volume of Gynecologic Pathology Expert Consultation Service with over 300% increase in volume from 2011 to 2016. ¿ Pathology coordinator: Interdisciplinary Gynecologic Oncologic Tumor Board. ¿ Medical Director of Gross rooms, Emory University Hospital and Emory University Hospital at Midtown.

    Honors / Awards:

    The Papanicolaou Society of Cytopathology Resident Research Award, 1st Place; March, 2017.,

    Golden Apple Award for contribution to Resident Education in Anatomic Pathology, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 2016-17.,

    AnnaLee Boyett Award in recognition of outstanding support to the Residency training program, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, June, 2018,

    Global Young Investigator Poster Award. Association for Molecular Pathology (AMP) Global Congress. April 5-7, 2017. Berlin, Germany.,

    Summa Cum Laude (University of Pecs Medical and Health Sciences Centre)., 2001

    Specialty Boards:

    2007  American Board of Pathology - Anatomical and Clinical Pathology

    2008  American Board of Pathology - Cytopathology

    2015  Recertified in Anatomic, Clinical and Cytopathology

    Selected Publications:

    Published and Accepted Research Articles -

    Fadare O, Desouki MM, Gwin K, Hanley KZ, Jarboe EA, Liang SX, Quick CM, Rawish KR, Roma A, Zheng W, Hecht JL, Parkash V, Osunkoya AO: Clear Cell Renal Cell Carcinoma Metastatic to the Gynecologic Tract: A Clinicopathologic Analysis of 17 Cases Int J Gynecol Pathol. 2018 Nov

    Wang XJ, Gwin K, Hanley KZ, Hecht JL, Jarboe EA, Liang SX, Quick V, Zheng W, Desouki MM, Fadare O: The Significance of L1CAM Expression in Clear Cell Carcinoma of the Endometrium, Histopathology. 2018 Feb;72(3):532-538.

    Hanley KZ, Dureau ZJ, Cohen C., Shin DM, Owonikoko TK, Sica GL: Orthopedia Homeobox (OTP) is preferentially expressed in typical carcinoids of the lung, Cancer Cytopathol. 2018 Apr;126(4):236-242

    Roe CJ, Hanley KZ: Updates in Cervical Cytology: The 90-Year-Long Journey from Battle Creek to Today.Surg Pathol Clin. 2018 Sep;11(3):589-599

    Terzic T1, Mills AM, Zadeh S, Atkins KA, Hanley KZ:GATA3 Expression in Common Gynecologic Carcinomas: A Potential Pitfall, Int J Gynecol Pathol. 2018 Jul 27.

    Sangoi AR, Kshirsagar M, Roma AA, Horvai AE, Chivukula M, Ellenson LH, Fadare O, Folkins AK, Garg K, Hanley K, Longacre T, Haas J, McCluggage WG, McKenney JK, Nucci MR, Oliva E, Park K, Parkash V, Quick CM, Rabban JT, Rutgers J, Soslow R, Vang R, Yemelyanova A, Zaloudek C, Beck AH: Interobserver Reproducibility Among Gynecologic Pathologists in Diagnosing Osteosarcomatous Components in Gynecologic Tract Carcinosarcomas Int J Gynecol Pathol. 2017 Jul;36(4):386-392

    Avadhani V, Hacihasanoglu E, Hanley KZ, Krishnamurti U, Krasinskas AM, Osunkoya AO, Daniels L, Freedman F, Goodman M, Adsay V, Reid M.: Cytologic Predictors of Malignancy in Bile Duct Brushings: A Multi-Reviewer Analysis of 60 Cases. Modern Pathology 2017 Sep;30(9):1273-1286

    Hanley KZ, Birdsong GG, Mosunjac MB:Recent Developments in Surgical Pathology of the Uterine Corpus,Arch Pathol Lab Med. 2017 Apr;141(4):528-541

    Martinez AP, Cohen C, Hanley K and Li XB: Estrogen receptor and Cytokeratin 5 are reliable markers to separate usual ductal hyperplasia from atypical ductal hyperplasia and low grade ductal carcinoma in situ, Arch Pathol Lab Med. 2016 Jul;140(7):686-9

    Hanley KZ, Fadare O, Fisher KE, Atkins KA, Mosunjac MB: Clinical significance of positive pelvic washings in uterine serous papillary carcinoma confined to an endometrial polyp Int J Gynecol Pathol. 2016 May;35(3):249-55.

    Rubinsak L, Cohen C, Khanna N, Horowitz I, Hanley KZ: Folate receptor alpha expression in platinum resistant/refractory ovarian carcinomas and primary endocervical adenocarcinomas Appl Immunohistochem Mol Morphol. 2016 Dec 9.

    Hanley KZ, Fadare O, Fisher KE, Atkins KA, Mosunjac MB: Clinical significance of positive pelvic washings in uterine serous papillary carcinoma confined to an endometrial polyp. Int. J. of Gynecol. Pathology (In press)

    Martinez AP, Cohen C, Hanley K and Li X: ER and CK5 are reliable markers to separate usual ductal hyperplasia from ADH and low grade DCIS. Archives of Pathology and Laboratory Medicine (accepted).

    Ciszak T, Mittal PK, Sullivan P, Cardona K, Hanley KZ, Khanna N, Moreno CC: MR imaging features of disseminated uterine leiomyosarcoma presenting 18 months after elective hysterectomy with morcellation. Abdom Imaging. 2015 Oct;40(7):2600-5

    Fata CR, Seeley E, Du L, Shyr Y, Parkash V, Zheng W, Hecht J, Quick C, Jarboe E, Desouki MM, Gwin K, Hanley K, Liang SX, Caprioli R, Fadare O: Are Clear Cell Carcinomas of the Ovary and Endometrium Phenotypically Identical? A Proteomic Analysis. Hum Pathol. 2015 Oct;46(10):1427-36.

    Hanley KZ, Oprea GI, Ormenisan C, Seydafkan S, Mosunjac MB: Atypical findings on cervicovaginal smear correlate with cervical involvement by Malignant Mixed Mullerian Tumors of the uterus. Acta Cytol. 2015 Oct;59(4):319-24.

    Moreno CC, Sullivan PS, Kalb BT, Tipton RG, Hanley KZ, Kitajima HD, Dixon WT, Votaw JR, Oshinski JN, Mittal PK: Magnetic resonance imaging of rectal cancer: staging and restaging evaluation. Abdom Imaging. 2015 Mar 11.

    Swadley MJ, Deliu M, Mosunjac MB, Gunthel CJ, Nguyen ML, Hanley KZ: Primary and Secondary Hepatic Lymphomas Diagnosed by Image-Guided Fine Needle Aspiration: A Retrospective Study of Clinical and Cytomorphological Findings. Am J Clin Pathol. 2014 Jan; 141(1):119-27

    Dulaney CB, Hall WA, Mikell JL, Mittal P, Prabhu RS, Kooby DA, Hanley K, Sarmiento JM, Landry JC: The Influence of Time Interval Between Diagnostic Image Acquisition and Operative Date on Pathologic Tumor Size In Pancreatic Adenocarcinoma: Implications for Local Therapy. Journal of Biomedical Graphics and Computing. 2014 Vol. 4 No 2: 15-22.

    Ezhapilli SR, Moreno CC, Small WC, Hanley K, Kitajima HD, Mittal PK: Mesenteric masses: Approach to differential diagnosis at MRI with histopathologic correlation. J Magn Reson Imaging. 2014 Oct;40(4):753-69

    Radzio J, Hanley KZ, Mitchell J, Ellis S, Deyounks F, Jenkins LT, Hanson D, Heneine W, Garcia-Lerma G: Depot-medroxyprogesterone acetate does not reduce the prophylactic efficacy of emtricitabine and tenofovir disoproxil fumarate in macaques J Acquir Immune Defic Syndr. 2014 Sep 8.

    Fadare O, Desouki MM, Gwin K, Hanley KZ, Jarboe EA, Liang SX, Quick SM, Zheng W, Parkash V, Hecht JL: Frequent Expression of Napsin A in Clear Cell Carcinoma of the Endometrium: Potential Diagnostic Utility. Am J Surg Pathol. 2014 Feb;38(2):189-96.

    Dun EC, Hanley KZ, Wieser F, Bohman S, Yu J, Taylor RN: Infiltration of Tumor-associated Macrophages is Increased in the Epithelial and Stromal Compartments of Endometrial Carcinomas. International Journal of Gynecologic Pathology. In press.

    Hall WA, Mikell JL, Mittal P, Colbert L, Prabhu RS, Kooby DA, Nickleach D, Hanley K, Sarmiento JM, Ali AN, Landry JC. Tumor Size on Abdominal MRI Versus Pathologic Specimen in Resected Pancreatic Adenocarcinoma: Implications for Radiation Treatment Planning. Int J Radiat Oncol Biol Phys. 2013 Jan 3

    Fadare O, Parkash V, Gwin K, Hanley KZ, Jarboe EA, Liang SX, Quick CM, Zheng W, Rawish KR, Hecht JL, Desouki MM.:Utility of Alpha-methylacyl-CoA-racemase (p504s) Immunohistochemistry In Distinguishing Endometrial Clear Cell Carcinomas from Serous and Endometrioid Carcinomas Hum Pathol. 2013 Dec;44(12):2814-21

    Mentrikoski MJ, Shah AA, Hanley KZ, Atkins KA. Assessing endometrial hyperplasia and carcinoma treated with progestin therapy. Am J Clin Pathol. 2012 Oct;138(4):524-34

    Kinsella MD, Birdsong GG, Siddiqui MT, Cohen C, Hanley KZ: Immunohistochemical Detection of Estrogen Receptor, Progesterone Receptor and Human Epidermal Growth Factor Receptor 2 in Formalin-Fixed Breast Carcinoma Cell block Preparations: Correlation of results to corresponding tissue block (needle core and excision) samples. Diagn Cytopathol. May 2012

    Dustin SM, Jo VY, Hanley KZ, Stelow EB.: High sensitivity and positive predictive value of fine-needle aspiration for uncommon thyroid malignancies. Diagn Cytopathol. 2011 Sep.

    KZ Hanley, MB Mosunjac: Diagnostic approach to hyperchromatic cell clusters on conventional and liquid-based Papanicolaou tests. ASCP Checksample, NO.C 10-7 (C-433), June, 2010.

    Hanley K.Z, Dustin SM, Stoler MH, Atkins KA: The significance of tumor involved andenomyosis in otherwise low-stage endometriod adenocarcinoma. Int. J. Gyn. Path. In press

    Jo VY, Stelow EB, Hanley KZ: Malignancy Risk for Fine-Needle Aspiration of Thyroid Lesions According to The Bethesda System for Reporting Thyroid Cytopathology Am. J Clin. Path. In Press

    KZ Hanley, MT Siddiqui, D Lawson, C Cohen, A Nassar: Rabbit Monoclonal Antibodies in Detection of ER, PR and Her2 in Breast Carcinoma Cell Block Sections by Conventional Microscopy and Quantitative Image Analysis Diagn Cytopathol. 2009 Feb 13.

    KZ Hanley, GG Birdsong, C Cohen, MT Siddiqui: Immunohistochemical Detection of Estrogen and Progesterone Receptors and HER2 Expression in Breast Carcinomas: Comparison on Cell Block, Needle Core and Tissue Block Preparations. Cancer Cytopathol. 2009 Aug 25;117(4):279-88

    KZ Hanley, SW Weiss, S Logani: Melanoma with cartilaginous differentiation: Diagnostic challenge on fine needle aspiration with emphasis on differential diagnosis Diagn Cytopathol. 2009 Jan;37(1):51-5.

    KZ Hanley, TS Tadros, AJ Briones, GG Birdsong, MB Mosunjac: Hematolymphoid malignancies of the female genital tract diagnosed on liquid-based Pap test: Cytomorphologic features and review of differential diagnosis Diagn Cytopathol. 2009 Jan;37(1):61-7

    Hanley K, Wang J, Bourne P, Yang Q, Gao AC, Lyman G, Tang P: Lack of expression of androgen receptor may play a critical role in the transformation from in situ to invasive basal subtype of high grade ductal carcinoma of the breast Human Pathology 2008 Mar; 39(3):386-92

    Hanley KZ, Facik MF, Bourne PA, Yang Q, Spaulding B, Bonfiglio TA, Xu H: Utility of Anti-L523S Antibody in the Diagnosis of Benign and Malignant Serous Effusions Cancer 2007 Dec 20;114 (1): 49-56.

    Pajor L, Kereskai L, Zsdral K, Nagy Z, Vass JA, Jakso P, Radvanyi G: Philadelphia chromosome and/or bcr-abl mRNA-positive primary thrombocytosis: morphometric evidence for the transition from essential thrombocythaemia to chronic myeloid leukaemia type of myeloproliferation. Histopathology. 2003 Jan;42(1):53-60.

    Other Publications -

    Hanley KZ: Rosen`s Breast Pathology (Book Review) American Journal of Surgical Pathology. 38(10):1450, October 2014.