Susan Muller, DMD

Oral Pathology

Associate Professor
Pathology & Laboratory Medicine

Other Appointments/Positions

Associate Professor, Otolaryngology Head & Neck Surgery, Emory University School of Medicine

Associate Professor, Winship Cancer Institute

Pathology Division(s):
Anatomic Pathology

Email Address:
susan.muller@emoryhealthcare.org

Education:

B.A. (Biology)   Rutgers University, NJ, 1974 - 1979

M.S. (Nutrition Science)   Drexel University, Philadelphia, PA, 1981 - 1983

D.M.D.   Medical University of South Carolina School of Dental Medicine, 1985 - 1989

  Post-Doctoral Research Fellow, Microbiology and Immunology Medical Univ. South Carolina, Charleston, 1989 - 1990

  Resident, Oral and Maxillofacial Pathology, Emory University School of Medicine, Atlanta, GA, 1990 - 1993

  Clinical Fellow, Head and Neck Pathology, Presbyterian University Hospital, Univ. of Pittsburgh Medical Center, 1993 - 1994

Research Interests:

- Overview
I collaborate with researchers at Winship Cancer Institute investigating molecular markers of oral cancer, including models of oral cancer metastasis. Another project is looking at predictors of malignant transformation of oral leukoplakia. Other research interests include participation in a chemoprevention trial for patients with oral dysplasias to see if this will impede transformation to oral cancer. Working closely with the Otolaryngologists on faculty, I am involved in the histologic typing of various head and neck tumors, particularly odontogenic and salivary gland tumors and how they relate to clinical outcomes.

Clinical Focus:

I am actively involved in the head and neck pathology service, which receives specimens from the metropolitan Atlanta region and outlying counties. I provide expert consultation in the typing of odontogenic cysts and tumors, salivary gland tumors, and unusual neoplasms of the upper aerodigestive tract.

Honors / Awards:

1989 - Omicron Kappa Upsilon, National Dental Honorary Society.,

Specialty Boards:

1994  American Board of Oral and Maxillofacial Pathology

Selected Publications:

Published and Accepted Research Articles -

Muller, Su L, Tighiouart M, Saba N, Zhang H, Shin DM, Chen Z. Distinctive E-cadherin and epidermal growth factor receptor expression in metastatic and non-metastatic head and neck squamous cell carcinoma: Predictive and prognostic correlation. Cancer 113, 97-107, 2008.

Muller S, Pan Y, Li R, Chi AC. Changing trends in the incidence of oral squamous cell carcinoma with particular reference to young patients, 1971-2006. The Emory University Experience. Head Neck Pathol 2, 60-66, 2008

McLean JN, Nunley SR, Klass C, Moore CE, M¿ller S, Johnstone PAS. Combined modality therapy of esthesioneuroblastoma. Otolaryngol- Head Neck Surg 136(6):998-1002, 2007.

Vigneswaran N, Baucum DC, Wu J, Lou Y, Bouquot J, Muller S, Wolfgang Zacharias. Repression of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) but not its receptors during oral cancer progression. BMC Cancer 7:108, 2007.

Penner CR, Muller S. Head & neck amyloidosis. A clinicopathologic study of 15 cases. Oral Oncology 42:421-429.

Fowler BZ, Muller S, Chen AY, Johnstone PAS. Factors influencing long-term survival after salvage total laryngectomy after initial radiotherapy or conservative surgery. Head Neck 28:99-106, 2006.

Vigneswaran N. Wu J. Muller S. Zacharias W. Narendran S. Middleton L. Expression analysis of cystatin C and M in laser-capture microdissectioned human breast cancer cells--a preliminary study. Pathol Res Prac 200(11-12):753-62, 2005

Chi AC, S Muller. Peripheral odontogenic keratocyst: A case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:71-78, 2005

Zhang X, JL Hunt, DP Landsittel, S Muller, K Adler-Storthz, RL Ferris, DM Shin, A Chen. Correlation of protease-activated receptor-1 (PAR-1) with differentiation markers in squamous cell carcinoma of the head and neck and its implication in lymph node metastasis. Clin Can Res 10: 8451-8459, 2004

Muller S, N Vigneswaran. Oral and maxillofacial pathology case of the month. Cicatricial pemphigoid (mucous membrane pemphigoid). Texas Dent J, 121:103, 2004.

DelGaudio JM, Muller S. Diagnosis and treatment of supraglottic laryngeal paraganglioma: Report of a case. Head Neck 26:94-98, 2004.

DelGaudio JM, Swain R, Kingdom TT, Muller S, Hudgins P. Computed tomographic findings in patients with invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 129:236-240, 2003

Wright JM, Vincent SD, Muller S, McClatchey KD, Budnick SD, Murrah VA. The future of oral and maxillofacial pathology. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:176-186, 2003.

Chi AC, Carey J, Muller S. Intraosseous schwannoma of the jaws: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96: 54-65, 2003.

Vigneswaran N, Muller S. Oral and maxillofacial pathology case of the month: dentin dysplasia type I. Texas Dental Journal, 119(12):1209, 1216, 2002.

Seyer B, Grist WJ, Muller S. Agressive, destructive midfacial lesion secondary to cocaine abuse. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:465-470, 2002.

McGuire DB, Peterson DE, Muller S, Owen DC, Slemmons MF, Schubert MM. The 20 item oral mucositis index: reliability and validity in bone marrow and stem cell transplant patients. Cancer Invest 20:893-903, 2002.

Behar P, Muller S, Todd W. Heterotopic Neuroglial Tissue Causing Airway Obstruction in the Newborn. Arch Otolaryngol Head Neck Surg 127:997-1002, 2001.

Dillard DG, Muller S, Cohen C, Bloch D, Del Gaudio JM, Gal AA. High tumor grade in salivary gland mucoepidermoid carcinoma correlates with loss of expression of transforming growth factor beta II receptor. Arch Otolaryngol Head Neck Surg 127:683-686, 2001.

Penner CR, S Muller, JM Del Gaudio. Clinicopathologic Conference: Diffuse parotid swelling. Oral Surg Oral Med Oral Pathol Oral Raiol Endod 91:8-11, 2001.

Swain RE Jr, Kingdom TT, DelGaudio JM, Muller S, Grist WJ. Meningiomas of the paranasal sinuses. Am J Rhinology 15:27-30, 2001.

Sharara N, Muller S, Olson J, Grist WJ, Grossniklaus HE. Sinonasal undifferentiated carcinoma (SNUC) with orbital invasion. Report of three cases. Ophthalmic Plastic Reconstructive Surg 17:288-292, 2001.

Cox DP, S Muller, G Carlson, D Murray. Ameloblastic carcinoma ex ameloblastoma of the mandible with malignancy associated hypercalcemia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90:716-722, 2000.

Vigneswaran N, W Zhao, A Dassanayake, S Muller, DM Miller, W Zacharias. Variable expression of cathepsin B and D correlates with highly invasive and metastatic phenotype of oral cancer. Hum Pathol 31:931-937,2000.

Swain R, T Kingdom, S Muller. Pathology forum: quiz case 3. Botryomycosis. Arch Otolaryngol Head Neck Surg 126:1155, 1159-1160, 2000

Dillard DG, C Cohen, S Muller, J DelGaudio, O Reichman, B Parrish, D Rackley, AA Gal. Immunolocalization of activated TGF-B1 in juvenile nasopharyngeal angiofibroma. Arch Otololaryngol Head Neck Surg 126:723-725, 2000.

Bayles S, W Todd, S Muller, D Rabkin. Pleomorphic adenoma of the pediatric tongue. Otolaryngol Head Neck Surg 120(6):934-936, 1999.

Whitaker E, D Cerenko, S Muller, P Hudgins. Multifocal Langerhans cell histiocytosis involving bilateral temporal bones, lungs, and hypothalamus in an adult. Skull Base Surg 9(1):51-56, 1999.

Behar PM, NW Todd, S Muller. Quiz case 2: Sinus histiocytosis with massive lymphadenopathy (SNHL). Arch Otolaryngol Head Neck Surg 125(12): 1399, 1401, 1999.

Behar P, F Albritton, S Muller, NW Todd. Multicentric infantile myofibromatosis. Int J Ped Otolaryngol 45:249-254, 1998

Book Chapters -

Muller S. Oral Precancer. In: Oral Cancer, Werning, J. W (ed.), Oral Cancer, Thieme, NY 2007; 8-18.

Muller S. Non-neoplastic lesions. In: LDR Thompson (ed), Head and Neck Pathology, Elsevier Science, Phila, PA 2006.

Muller S. Non-infectious ulcerative and vesiculoerosive lesions of the oral cavity. In: L. Barnes (ed.), Surgical Pathology of the Head and Neck, Marcel Dekker, NY, second edition, 2001; 301-341

Muller S, CA Waldron. Premalignant Lesions of the Oral Cavity. In: L. Barnes (ed.), Surgical Pathology of the Head and Neck, Marcel Dekker, NY, second edition, 2001; 343-368

Other Publications -

Murray N, Muller S, Amedee RG. Ulcerative Lesions of the Oral Cavity. Self-Instructional Package, American Academy of Otolaryngology-Head and Neck Surgery Foundation, Inc., Alexandria, VA, first edition, 2000.