Egelston Hospital, 1405 Clifton Rd.
404 785-6499 Phone
Professor of Pediatrics, Emory University School of Medicine
MD Assiut University School of Medicine, Assuit, Egypt, 1963 - 1970
Internship Assuit University Hospitals. Assuit, Egypt, 1971 - 1972
Residency Internal Medicine, Ministry of Health Hospitals, Assuit, Egypt, 1972 - 1976
Residency Anatomic and Clinical Pathology, Aultman Hospital, Canton, OH, 1983 - 1987
Fellowship Pediatric and Fetal Pathology, Children's Hospital Medical Center of Akron, Akron, OH, 1987 - 1989
- Childhood Tumors
Dr. Shehata has begun to integrate genomics, proteomics, metabolomics etc. into tumor characterization studies. Under the direction of Dr. Shehata, the Department of Pathology at Children's Healthcare of Atlanta (CHOA) created a tumor bio-repository (tumor bank) in 2003. Dr. Shehata uses his tumor bank and new sequencing technologies to characterize the cancer genome, identify candidate genes that denote class of diagnosis, prognosis, and potential therapeutic targets, and ultimately help pediatric oncology physicians and scientists develop targeted molecular therapies. Recently, he and his team identified angiogenic genes that contribute to the development of Alveolar Soft Part Sarcoma. These novel results were presented in a platform presentation entitled "Molecular Analysis of Alveolar Soft Part Sarcoma (ASPS) Identifies A Strong Angiogenic Gene Expression Impacting Gene Targeted Therapy" at an international pathology meeting. Future studies will continue to understand the role of angiogenic genes in tumor development.
- Hirschsprung Disease
Dr. Shehata has developed a new staining method for expedient diagnosis of Hirschsprung disease and other forms of intestinal dysmotility in children. This new method has recently been submitted for publication.
- Histiocytoid Cardiomyopathy Registry
Histiocytoid Cardiomyopathy (HC) is Dr. Shehata's primary research project, which he has been focused on for over 20 years. By creating an HC registry and collecting over 120 cases, he has been able to identify two potential genes responsible for HC. Additionally, knowing the complexity of this heterogenous disease, he performed whole exome sequencing and recently identified two new causative genes. Dr. Shehata presented his data in Europe as a platform presentation entitled "Knockdown of ndufb11 in Zebrafish Model Results in Cardiac Anomalies, Confirming the Role of the Newly Recognized NDUFB11 in Histiocytoid Cardiomyopathy Pathogenesis," which was well received by the international community. Dr. Shehata continues to research HC and is now focused on the familial inheritance pattern, which represents 5% of all known cases of HC. He plans to extend this project into the adult population by studying arrhythmia of unknown etiology.
- Neuroblastoma Analysis
Dr. Shehata is collaborating with a biomedical engineering team at Georgia Tech to analyze certain subtypes of neuroblastomas. The aim is to compare anaplastic variant to conventional stroma rich variants. Together they will utilize mass spectrometry and whole image slide processing in order to understand the molecular/genetic base of the anaplastic variant.
- Causes of Still Birth
Through a nationwide NIH grant, we performed fetal and placental evaluation in an attempt to find causes of unexplained still births. Several publications were produced from this study.
- Osteosarcoma Research
Dr. Shehata has been collecting tumor samples from osteosarcoma patients (pre-treatment, post-treatment, and cultured fibroblasts). A comparative genomic hybridization study is in progress for those patients who had these three components saved in the bio-repository focusing to understand the mechanism and predisposition to osteosarcoma.
- Billiary Atresia
Dr. Shehata and his colleague Dr. Abramowsky represent Emory/CHOA in a multi-center consortium studying the billiary remnants from infants who were diagnosed with billiary atresia in an attempt to identify the underlying cause. The group meets 3-4 times per year to review a collection of those remnants.
- Cardiovascular Pathology
In addition to Dr. Shehata's Histiocytoid Cardiomyopathy research, he is studying two other forms of cardiomyopathy including Adriamycin Induced Cardiomyopathy and Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia. Furthermore, his interest in cardiovascular pathology extends to the reason for graft failure for which he co-authored the results showing that cardiac steatosis can lead to a deleterious outcome in those patients. The focus now is using the molecular means to evaluate the relation between chimerism and graft failure. The preliminary data was presented in an international meeting showing that chimerism can lead to graft failure. The manuscript is in progress. Finally, Dr. Shehata and his team are utilizing whole slide image signal processing of cardiac biopsies of transplant patients to identify a more accurate and producible method to grade the degree of rejection.
I practice and teach in the area of pediatric anatomic pathology, primarily at the Egleston campus of Children's Healthcare of Atlanta and Emory University School of Medicine. My primary focus is in the area of cardiovascular pathology in general, and specifically in Histiocytoid Cardiomyopathy where I have created a world wide registry. In addition, I focus in childhood tumors with an emphasis in diagnostic, molecular and genetic basis. Furthermore, I have developed an internship program where I mentor pre-med students and medical students to prepare them for their medical training. Some of these students came from outside of the United States to join my internship program. All of my students participate in clinical research, international presentations and publications throughout their internship.
Harry B. Neustein Award for "Knockdown of ndufb11 in Zebrafish Model Results in Cardiac Anomalies, Confirming the Role of the Newly Recognized NDUFB11 in Histiocytoid Cardiomyopathy Pathogenesis.", 2014
Harry B. Neustein Award for "Identification of Candidate Gene for Histiocytoid Cardiomyopathy Using While-Genome Analysis: Analyzing Material From the HC Registry.", 2010
Harry B. Neustein Award for "Ewing Sarcoma with 7:22 Translocation- Is it Occurring in a Younger Age Group with Predilection for Extraskeletal Location? A Study of 35 Cases with Emphasis on Molecular Analysis.", 2008
1992 Diplomate Anatomic Pathology, American Board of Pathology
1993 Diplomate Pediatric Pathology, American Board of Pathology
Bezerra JA, Spino C, Magee JC, Shneider BL, Rosenthal P, Wang KS, Erlichman J, Haber B, Hertel PM, Karpen SJ, Kerkar N, Loomes KM, Molleston JP, Murray KF, Romero R, Schwarz KB, Shepherd R, Suchy FJ, Turmelle YP, Whitington PF, Moore J, Sherker AH, Robuck PR, Sokol RJ; Childhood Liver Disease Research and Education Network (ChiLDREN). Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial. The Journal of the American Medical Association. 2014 May 7;311(17):1750-9.
Bukowski R, Hansen NI, Willinger M, Reddy UM, Parker CB, Pinar H, Silver RM, Dudley DJ, Stoll BJ, Saade GR, Koch MA, Rowland Hogue CJ, Varner MW, Conway DL, Coustan D, Goldenberg RL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Stillbirth Collaborative Research Network. Fetal growth and risk of stillbirth: a population-based case-control study. PLoS Medicine. 2014 Apr 22;11(4):e1001633.
Varner MW, Silver RM, Rowland Hogue CJ, Willinger M, Parker CB, Thorsten VR, Goldenberg RL, Saade GR, Dudley DJ, Coustan D, Stoll B, Bukowski R, Koch MA, Conway D, Pinar H, Reddy UM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Stillbirth Collaborative Research Network. Association between stillbirth and illicit drug use and smoking during pregnancy. Obstetrics and Gynecology. 2014 Jan;123(1):113-25.
Pinar H, Goldenberg RL, Koch MA, Heim-Hall J, Hawkins HK, Shehata B, Abramowsky C, Parker CB, Dudley DJ, Silver RM, Stoll B, Carpenter M, Saade G, Moore J, Conway D, Varner MW, Hogue CJ, Coustan DR, Sbrana E, Thorsten V, Willinger M, Reddy UM. Placental findings in singleton stillbirths. Obstetrics and Gynecology. 2014 Feb;123(2 Pt 1):325-36.
Archer SR, Abramowsky CR, Kobrynski L, Simoneaux S, Vogler LB, Ricketts RR, Parker C, Elawahbdeh N, Shehata BM. Malakoplakia and Primary Immunodeficiency. Journal of Pediatrics.Nov. 2014.
Shah A, Karass M, Page AJ, Durham M, Shehata BM. "Extra-hepatic bile duct hamartoma in a 10-month-old with a morgagni hernia and multiple anatomical anomalies: a rare and incidental finding." Pediatric Surgery International. 2013 Jul;29(7):745-8.
Talebagha S, Rizk K, Elawabdeh N, Fujuti W, Abramowsky CR, Shehata BM. Usefulness of OCT4/3 immunostain in pediatric malignant germ cell tumors. Fetal and Pediatric Pathology. 2013 Apr; 32(2):82-7. (EPub 2012 Apr 16).
Natarajan B, Saure C, Shehata B, Kugathasan C. Hidradenitis suppurativa and pediatric Crohn's disease: a case series. Journal of Pediatric Gastroenterology and Nutrition. 2013 Oct 10. (EPub ahead of print).
Conway DL, Hansen NI, Dudley DJ, Parker CB, Reddy UM, Silver RM, Bukowski R, Pinar H, Stoll BJ, Varner MW, Saade GR, Hogue C, Willinger M, Coustan D, Koch MA, Goldenberg RL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Stillbirth Collaborative Research Network (Shehata BM, Abramowsky CR)."An algorithm for the estimation of gestational age at the time of fetal death.¿ Paediatric Perinatal Epidemiology. 2013 Mar;27(2):145-57.
Sundaram SS, Alonso EM, Haber B, Magee JC, Fredericks E, Kamath B, Kerkar N, Rosenthal P, Shepherd R, Limbers C, Varni JW, Robuck P, Sokol RJ; Childhood Liver Disease Research and Education Network (Children). Health-related quality of life in patients with biliary atresia surviving with their native liver. Journal of Pediatrics. 2013 Oct;163(4):1052-7.
Leu SB, Shulman SC, Steelman CK, Lamps LW, Bulut OP, Abramowsky CR, Gold BD, Stockwell C, Havens J, Shehata BM. Pathogenic Yersinia DNA in intestinal specimens of pediatric patients with Crohn's disease. Fetal and Pediatric Pathology. 2013 Oct;32(5):367-70.
Jactel SN, Talebagha S, Langberg KM, Elawabdeh N, Abramowsky CR, Schniederjan M, Durham M, Ricketts RR, Pandya S, Clifton MS, Shehata BM. "Non-iatrogenic neonatal gastric perforation: the role of interstitial cells of Cajal." Fetal and Pediatric Pathology Journal. 2013 Dec;32(6):422-8.
White LJ, Shehata BM, Rajan R. Hairy polyp of the anterior nasal cavity. Otolaryngology - Head and Neck Surgery. 2013 Dec;149(6):961-2. (EPub 2013 Sep 25).
Kim HJ, Wojno T, Grossniklaus HE, Shehata BM. Alveolar soft-part sarcoma of the orbit: 2 case reports and a review of the literature. Ophthalmic Plastic and Reconstructive Surgery. 2013 Nov-Dec;29(6):2138-42.
Elawabdeh N, Sobol SE, Blount AC, Shehata BM. Unusual presentation of extracardiac fetal rhabdomyoma of the larynx in a pediatric patient with tuberous sclerosis. Fetal and Pediatric Pathology. 2013 Feb;31(1):43-7. (EPub 2012 Apr 12).
Ozlem PB, Romero R, Mahle WT, McConnel M, Braithwaite K, Shehata BM, Gupta NA, Vos, M, Alazraki A. "Magnetic resonance imaging identifies unsuspected liver abnormalities in patients after the Fontan procedure." The Journal of Pediatrics. 2013 Jul;163(1):201-6.
Elawabdeh N, Cone BM, Abramowsky CR. MD, Wrubel DM, Grossniklaus HE, Walrath JD, Geaghan SM, Bashir MZ, Shehata BM. Epstein-Barr virus associated smooth muscle tumors in post-transplant pediatric patients. Three cases of rare location and review of the literature. Fetal and Pediatric Pathology. 2013 June;32(3):184-91. (EPub 2013 Feb 27).
Ballisty MM, Braithwaite KA, Shehata BM, Dickson PN. Imaging findings in megacystis microcolon intestinal hypoperistalsis syndrome, a rare disease. Pediatric Radiology. 2013 April;43(4):454-9.
Salinas M, Elawabdeh N, Lin J, Naguib MM, Hodge MG, Shehata BM. The spectrum of pulmonary malformation in trisomy-21 patient, a review with emphasis on the molecular-genetic basis. Fetal and Pediatric Pathology. 2013 Feb;31(1):38-42. (EPub 2012 Apr 12).
Bulut OP, Abramowsky CR, Shehata BM, Romero R. Clinicopathologic findings in children with hepatopulmonary syndrome. Fetal and Pediatric Pathology. 2013 Jul;32(4):253-8.
Reddy UM, Page GP, Saade GR, Silver RM, Thorsten VR, Parker CB, Pinar H, Willinger M, Stoll BJ, Heim-Hall J, Varner MW, Goldenberg RL, Bukowski R, Wapner RJ, Drews-Botsch CD, O'Brien BM, Dudley DJ, Levy B; NICHD Stillbirth Collaborative Research Network. Karyotype versus microarray testing for genetic abnormalities after stillbirth. New England Journal of Medicine. 2012 Dec 6;367(23):2185-93.
Lin J, Steelman CK, Durham M, Ricketts RR, Abramowsky CA, Shehata BM. Hepatic pulmonary fusion: two cases with diaphragmatic hernia and one case with Pentalogy of Cantrell. Fetal and Pediatric Pathology. 2012 Dec; 31(6):401-9. (EPub 2012 Apr 12).
McElroy AK, Hilinski JA, Abramowsky CR, Jaffe R, Park SI, Shehata BM, Cooper TM. "Bacillary angiomatosis in patients with underlying malignancy: a pediatric case report and a review of the literature." Journal of the Pediatric Infectious Diseases Society. 2012; 1-4.
Shulman SC, Katzenstein HM, Bridge J, Bannister LL, Qayed M, Oskouei S, Shehata BM. Ewing sarcoma with 7;22 translocation: three new cases with clinicopathological characterization. Fetal and Pediatric Pathology. 2012 Dec;31(6):341-8. (EPub 2012 Mar 20).
Rostad CA, McElroy AK, Hilinski JA, Thompson MP, Drew CP, Denison AM, Zaki SR, Mahle WT, Rogers J, Abramowsky CR, Shehata B. Bartonella henselae-mediated disease in solid organ transplant recipients: two pediatric cases and a literature review. Transplant Infectious Disease. 2012 Oct;14(5):E71-81.
Shulman SC, Chiang F, Steelman CK, Chiang KY, Haight A, Gow KW, Shehata BM. Pneumatosis intestinalis in pediatric hematopoietic stem cell transplantation patients: an uncommon complication. Fetal and Pediatric Pathology. 2012 Oct;31(5):309-14. (EPub 2012 Mar 20).
Wang J, Shehata BM, Langness SM, Davis A, Cheng L, Osunkoya AO. Clear cell, papillary and chromophobe renal cell carcinoma in patients younger than 20 years old: A clinicopathologic study with follow-up. Journal of Pediatric Urology. 2012 Oct;8(5):531-4. (EPub 2011 Oct 20).
Rogers J, Steelman CK, Procop GW, Abramowsky CR, Tuohy MT, Shehata BM. Clinical utility of DNA amplification and sequencing to identify a strain of Mycobacterium avium in paraffin-embedded, formalin-fixed biopsies from an immunosuppressed child. Pediatric and Developmental Pathology. 2012 Jul-Aug;15(4):315-7. (EPub 2012 May 2).
Cone BM, Taweevisit M, Shenoda S, Sobol S, Schemankewitz E, Shehata BM. Pharyngeal hairy polyps: five new cases and review of the literature. Fetal and Pediatric Pathology. 2012 Jun;31(3):184-9. (Epub 2012 Mar 13).
Hodge MG, Ricketts RR, Simoneaux SF, Abramowsky CR, Elawabdeh N, Shehata BM. Splenic cysts in pediatric population: A report of 21 cases with review of the literature. Fetal and Pediatric Pathology. 2012 Apr;31(2):54-62.
Naguib MM, Abramowksy CR, Lin J, Shehata BM. Spinal cysticercosis mimicking a tumor in a pediatric patient. Fetal and Pediatric Pathology. 2012 Apr;31(2):50-3.
Polsani A, Braithwaite KA, Alazraki AL, Abramowsky CR, Shehata BM. NUT midline carcinoma: an imaging case series and review of literature. Pediatric Radiology. 2012 Feb;42(2):205-10. (Epub 2011 Oct 28).
Steelman CK, Bannister LL, Palmer MB, Chang TS, Elawabdeh N, Shehata BM. Nephrogenic rest within a lipomyelomeningocele in a patient with unilateral renal agenesis. Fetal and Pediatric Pathology. 2012Aug;31(4):260-4. (EPub 2012 Mar 20).
Gonzalez RS, Shulman SC, Katzenstein HM, Steelman CK, Wulkan ML, Abramowsky CR, Cohen C, Davis GK Shehata BM. Colorectal adenocarcinoma: a pediatric case review with a focus on mismatch repair gene mutations and E-cadherin expression. Pediatric and Developmental Pathology. 2012 May-Jun;15(3):192-8. (EPub 2011 Oct 10).
Thomason JL, Abramowsky CR, Rickets RR, Culbertson JH, Clifton MS, Shehata BM. Proteus Syndrome: three case reports with a review of the literature. Fetal and Pediatric Pathology. 2012 Jun;31(3): 145-53. (EPub 2012 Mar 13).
Sullivan HC, Olson TA, Ricketts RR, Oskouei SV, Shehata BM. Unusual presentation of metastatic Ewing sarcoma to the ovary in a 13 year-old: a case report and review. Fetal and Pediatric Pathology. 2012 Jun;31(3): 159-63. (Epub 2012 Mar 13).
DeBoer EM, Keene S, Shehata BM. Identical twins with lethal congenital pulmonary airway malformation type 0 (acinar dysplasia): further evidence of familial tendency. Fetal and Pediatric Pathology. 2012 Aug;31(4):217-24. (EPub 2012 Mar 13).
Grossniklaus HE, Shehata B, Sorensen P, Bergstrom C, Hubbard GB. Primitive neuroectodermal tumor/Ewing sarcoma of the retina. Archives of Pathology & Laboratory Medicine. 2012 Jul;136(7):829-31.
Fujita AW, Steelman CK, Abramowsky CR, Ricketts RR, Durham MM, Clifton MS, Pandya SR, Shehata BM. Ciliated hepatic foregut cyst: four case reports with a review of the literature. Pediatric and Developmental Pathology . 2011Sep-Oct;14(5),418-21. (EPub 2011 April 14).
Shehata BM, Bouzyk M, Shulman SC Tang W, Steelman CK, Davis GK, Moreno CS. Identification of candidate genes for histiocytoid cardiomyopathy (HC) using whole genome expression analysis: analyzing material from the HC registry. Pediatric and Developmental Pathology. 2011 Sept-Oct;14(5), 370-7. (EPub 2011 May 17).
Pinar H, Koch M, Hawkins H, Heim-Hall J, Shehata BM, Thorsten VR, Chin S, Willinger M, dela Monte S. The Stillbirth Collaborative Research Network (SCRN) neuropathologic examination protocol. American Journal of Perinatology. 2011 Dec;28(10):793-802. (EPub 2011 Jul 21).
Shulman SC, Broecker JS, Abramowsky CR, Katzenstein HM, Wulkan ML, Shehata BM. Unusual presentation of Rosai-Dorfman disease (RDD) in the bone in adolescents. Fetal and Pediatric Pathology. 2011;30(6):442-7. (EPub 2011 Oct 25).
Shehata BM, Elmore JM, Bootwala Y, Steelman CK, Shoffeitt CJ, Wang R, Zhau HE, He D, Zhu G, Chung LW. Immunohistochemical characterization of sonic hedgehog and its downstream signaling molecules during human penile development. Fetal and Pediatric Pathology. 2011;30(4):244-51. (EPub 2011 Mar 24).
Parker CB, Hogue CJ, Koch MA, Willinger M, Reddy UM, Thorsten VR, Dudley DJ, Silver RM, Coustan D, Saade GR, Conway D, Varner MW, Stoll B, Pinar H, Bukowski R, Carpenter M, Goldenberg R; Stillbirth Collaborative Research Network. Stillbirth Collaborative Research Network: design, methods and recruitment experience. Paediatric Perinatal Epidemiology. 2011 Sep;25(5):425-35.
Sacks JH, Mahle WT, Steelman CK, Abramowsky CR, Kanter KR, Vincent RN, Berg A, Shehata BM. Fibrofatty changes in failed pediatric cardiac allografts. Pediatric and Developmental Pathology. 2011 May-Jun;14(3):194-7. (EPub 2010 Nov 9).
Schuetz AN, Guarner J, Packard MM, Zaki SR, Shehata BM, Opreas-Ilies G. Infectious disease immunohistochemistry in placentas from HIV-positive and HIV-negative patients. Pediatric and Developmental Pathology. 2011 May-Jun;14(3):180-8. (EPub 2010 Nov 5).
Brown J, Shehata BM, Campbell R. Atresia of abdominal aorta in neonate with recanalization and development of normal aortic architecture: case report and review of literature. Congenital Heart Disease. 2011 May;6(3):280-3. (EPub 2011 Mar 16).
Lin J, Shulman SC, Steelman CK, Oskouei SV, Reith JD, Simoneaux SF, Olson TA, Shehata BM. Fibrocartilaginous mesenchymoma, a unique osseous lesion: case report with review of the literature. Skeletal Radiology 2011;Nov 40(11):1495-9. (EPub 2011 May11).
Shulman SC, Shehata BM. Amniotic band syndrome: characteristic manifestations of ABS in three cases. Pathology Case Reviews. 2011; 16(5): 195-197.
Kogon B, Shehata BM, Katzenstein H, Samai C, Mahle W, Maher K, Olson T. Primary congenital infantile fibrosarcoma of the heart: the first confirmed case. Ann Thorac Surg. 2011 Apr;91(4):1276-80.
Steelman CK, Katzenstein H, Parham DM, Stockwell CA, Ricketts RR, Abramowsky CR, Bridge JA, Sorenson PH, Kenney BD, Olson TA, Igbokwe A, Lopez-Terrada DH, Shehata BM. Unusual presentation of congenital infantile fibrosarcoma (CIFS) in seven infants with molecular-genetic analysis. Fetal and Pediatric Pathology. 2011;30(5):329-37. (EPub 2011 Aug 15).
Shehata BM, Gupta NA, Katzenstein HM, Steelman CK, Wulkan ML, Gow KW, Bridge JA, Kenney BD, Thompson K, de Chadarevian JP, and Abramowsky CR. Undifferentiated embryonal sarcoma of the liver is associated with mesenchymal hamartoma and multiple chromosomal abnormalities: a review of eleven cases. Pediatric and Developmental Pathology. 2011 Mar-Apr;14(2):111-6. (EPub 2010 Oct 6).
Deyrup AT, Miettinen M, North PE, Khoury JD, Tighiouart M, Spunt SL, Parham D, Shehata BM, Weiss SW. Pediatric Cutaneous Angiosarcomas: a clinicopathologic study of 10 cases. American Journal of Surgical Pathology. 2011; Jan 35(1):70-5.
Broecker JS, Steelman CK, Broecker BH, Shehata BM. Nephrogenic adenoma of the bladder in a prune belly syndrome patient: case report and review of the literature. Fetal and Pediatric Pathology. 2011;30(5):296-300. (EPub 2011 Aug 15).
Chang TS, Ricketts RR, Abramowsky CR, Cotter BD, Steelman CK, Husain A, Shehata BM. Mesenteric cystic masses: a series of 21 pediatric cases and review of the literature. Fetal and Pediatric Pathology. 2011;30(1):40-4.
Shehata BM, Chang TS, Greene CE, Steelman CK, McHugh MC, Zarroug A, Ricketts R. Gastric heterotopia with extensive involvement of the small intestine associated with congenital short bowel syndrome and intestinal malrotation. Fetal and Pediatric Pathology. 2011;30(1):60-3.
Pinar H, Koch MA, Hawkins H, Heim-Hall J, Shehata BM, Thorsten VR, Carpenter M, Lowichik A, Reddy UM. The Stillbirth Collaborative Research Network (SCRN) placental and umbilical cord examination protocol. American Journal of Perinatology. 2011 Dec;28(10): 781-92. (EPub 2011 Jun 29).
Shehata BM, Katzenstein HM, Abramowsky CR, Steelman CK, French CA, Saxe DF, Rickets RR, Olson TA. NUT midline carcinoma in a newborn with multiorgan disseminated tumor and a 2-year-old with a pancreatic/hepatic primary. Pediatric and Developmental Pathology. 2010 Nov-Dec;13(6):481-5. (EPub 2009 Dec 17).
Coto-Puckett WL, Gilbert-Barness E, Steelman CK, Stuart T, Robinson HB, Shehata BM. A spectrum of phenotypical expression of Neu-Laxova syndrome: Three case reports and a review of the literature. Fetal and Pediatric Pathology. 2010 Jan;29(2):108-19.
Oster M, Kogon B, Shehata BM, Fyfe D. Cyanosis in an eight-week-old infant. Journal of the Medical Association of Georgia. 2010;99(4):23.
Gow KW , Koontz CS, Dickson P, Bannister L, Shehata BM. Retropleural teratoma presenting as an abdominal mass in a 9-month old boy. Journal of Pediatric Surgery. 2010 Nov;45(11):E15-8.
Wang J, Steelman CK, Richburg DA, Chang T, Shehata BM. Two cases of anophthalmia and congenital heart disease: Adding a new dimension to this association. Fetal and Pediatric Pathology. 2010;29(5):291-8.
Summers R, Shehata BM, Stockwell C, Rapkin L. Mucinous adenocarcinoma of the lung in association with congenital pulmonary airway malformation. Journal of Pediatric Surgery. 2010 Nov;45(11):2256-9.
Abramowsky CR, Katzenstein HM, Alvarado CS, Shehata BM. Anaplastic large cell neuroblastoma. Pediatric and Developmental Pathology. 2009 Jan-Feb;12(1):1-5.
Fanaian NK, Cohen C, Waldrop S, Wang J, Shehata BM. Epstein-Barr virus (EBV)-encoded RNA: automated in-situ hybridization (ISH) compared with manual ISH and immunohistochemistry for detection of EBV in pediatric lymphoproliferative disorders. Pediatric and Developmental Pathology. 2009 May-Jun;12(3):195-9.
Deyrup AT, Miettinen M, North PE, Khoury JD, Tighiouart M, Spunt SL, Parham D, Weiss SW, Shehata BM. Angiosarcomas arising in the viscera and soft tissue of children and young adults: a clinicopathologic study of 15 cases. American Journal of Surgical Pathology. 2009 Feb;33(2):264-9.
Downs-Kelly E, Shehata BM, Lopez-Terrada D, Patel RM, Hartke M, Folpe AL, Tubbs RR, Skacel M, Goldblum JR. The utility of FOXO1 fluorescence in situ hybridization (FISH) in formalin-fixed paraffin-embedded specimens in the diagnosis of alveolar rhabdomyosarcoma. Diagnostic Molecular Pathology. 2009 Sep;18(3):138-43.
Zuckerman JD, Shehata BM, Hill CH, Sobol SE. Invasive laryngeal carcinoma in a 15-year-old with neglected papillomatosis. The International Journal of Otorhinolaryngology. 2009;8(2).
Oster M, Kogon B, Shehata BM, Fyfe D. Right atrial fibroma requiring emergent intervention in an 8-week-old infant. Congenital Heart Disease. 2009 May-Jun;4(3):190-2.
Shehata BM, Fishman I, Gow KW, Collins MH, Poulik JM, Ricketts RR, Wang J, Parker PM, Heiss KF, Bhatia A, Worcester HD. Pseudoangiomatous stromal hyperplasia of the breast in pediatric patients: an underrecognized entity. Pediatric and Developmental Pathology. 2009 Nov-Dec;12(6):450-4.
Schniederjan MJ, Shehata BM, Barr F, Brat DJ, Mapstone T, Esiashvili N, Marchs R, Stockwell CA, Janss AJ. De novo germline TP53 mutation presenting with synchronous malignancies of the central nervous system. Pediatric Blood and Cancer. 2009 Dec 15;53(7):1352-4.
Eskander BS, Shehata BM. Fraser syndrome: a new case report with review of the literature. Fetal and Pediatric Pathology. 2008;27(2):99-104.
Frem JC, Gold BD, Shehata BM, Cole CR. Reflux masquerader: acute Helicobacter pylori infection in neonates and infants. Journal of Pediatric Gastroenterology and Nutrition. 2008 May;46(5):589-92.
79. Chang TS, Shehata BM, Stallings C, Onyeije CI, Gow KW. Fetus in fetu presenting as an abdominal mass in a newborn female infant. The American Surgeon. 2008 Sep;74(9):883-5.
Shehata BM, Otto KJ, Sobol SE, Stockwell CA, Foulks C, Lancaster W, Gregoire L, Hill CE. E6 and E7 oncogene expression by human papilloma virus (HPV) and the aggressive behavior of recurrent laryngeal papillomatosis (RLP). Pediatric and Developmental Pathology. 2008 Mar-Apr;11(2):118-21. (EPub 2007 Apr 20).
Shehata BM, Stockwell CA, Castellano-Sanchez AA, Setzer S, Schmotzer CL, Robinson H. Von Hippel-Lindau (VHL) disease: an update on the clinico-pathologic and genetic aspects. Advances in Anatomic Pathology. 2008 May;15(3):165-71.
Cribbs R, Shehata BM, Ricketts R. Primary ovarian rhabdomyosarcoma in children. Pediatric Surgery International. 2008 May;24(5):593-5. (EPub 2007 Nov 15).
Schmotzer C, Shehata BM. Two cases of agnathia (otocephaly): with review of the role of fibroblast growth factor (FGF8) and bone morphogenetic protein (BMP4) in patterning of the first branchial arch. Pediatric and Developmental Pathology. 2008 Jul-Aug;11(4):321-4. (EPub 2008 Jan 3).
Bare JB, Abramowsky, CA, Denton TD, Dykes FD, Shehata BM. Perforation of the superior vena cava during ECMO catheterization in two neonates with congenital diaphragmatic hernia: a cause of accidental death. American Journal of Forensic Medical Pathology. 2008 Sep;29(3):271-3.
Stallings CL, Shehata BM, Wang J, Chang TS, Ricketts RR. Unusual presentation of ovarian cellular fibroma coexisting with nodular sclerosing Hodgkin's disease: a case report and review of the literature. Journal of Pediatric Surgery 2008 Sep;43(9):1722-5.
Gow KW, Rapkin LB, Olson TA, Durham MM, Wyly B, Shehata BM. Sentinel lymph node biopsy in the pediatric population. Journal of Pediatric Surgery. 2008 Dec;43(12):2193-8.
Graham JK, Shehata BM. Sudden death due to dissecting pulmonary artery aneurysm: a case report and review of the literature. The American Journal of Forensic Medicine and Pathology. 2007 Dec;28(4):342-4.
Ashrafi AH, Wang J, Stockwell CA, Lloyd D, McAlvin JB, Russo P, Shehata BM. Kawasaki disease: four case reports of cardiopathy with an institutional and literature review. Pediatric and Developmental Pathology. 2007 Nov-Dec;10(6):491-9.
Bare JB, Abramowsky CR, Hayes LL, Shehata BM. Congenital immature teratoma of the central nervous system: three case reports with literature review. Fetal and Pediatric Pathology. 2007 May-Jun;26(3):109-18.
84. Brat DJ, Shehata BM, Castellano-Sanchez AA, Hawkins C, Yost RB, Greco C, Mazewski C, Janss A, Ohgaki H, Perry A. Congenital glioblastoma: a clinicopathologic and genetic analysis. Brain Pathology. 2007 Jul;17(3):276-81. (EPub 2007 Apr 23).
Zhu G, Zhau HE, He H, Zhang L, Shehata BM, Wang X, Cerwinka WH, Elmore J, He D. Sonic and desert hedgehog signaling in human fetal prostate development. The Prostate. 2007 May 1;67(6):674-84.
Saad Df, Shehata BM, Patrick E, Gow KW: Intramolecular Hemangioma of the Abdominal Wall. Journal of Pediatric Surgery 2006; 41:601-602.
Chung LW, Huang WC, Sung SY, Wu D, Odero-Marah V, Nomura T, Shigemura K, Miyagi T, Seo S, Shi C, Molitierno J, Elmore J, Anderson C, Isotani S, Edlund M, Hsieh CL, Wang R, Shehata BM, Zhau HE. Stromal-epithelial interaction in prostate cancer progression. Clinical Genitourinary Cancer. 2006 Sep;5(2):162-70.
Brady AN, Shehata BM, Fernhoff PM. X-linked fetal cardiomyopathy caused by a novel mutation in the TAZ gene. Prenatal Diagnosis. 2006 May;26(5):462-5.
McMann LP, Kirsch AJ, Scherz HC, Smith EA, Jones RA, Shehata BM, Kozielski R, Grattan-Smith JD. Magnetic resonance urography in the evaluation of prenatally diagnosed hydronephrosis and renal dysgenesis. The Journal of Urology. 2006 Oct;176(4 Pt 2):1786-92.
Schuetz AN, Rubin BP, Goldblum JR, Shehata BM, Weiss SW, Liu W, Wick MR, and Folpe AL. Intercellular Junction Protein Expression in Ewing Sarcoma/Primitive Neuroectodermal Tumor: Additional Evidence of Epithelial Differentiation. Modern Pathology 2006 Nov; 18(11):1403-10.
Shehata BM, Bare JB, Denton TD, Habib MN, Black JO. Premature closure of the ductus arteriosus: variable response among monozygotic twins after in utero exposure to indomethacin. Fetal and Pediatric Pathology. 2006 May-Jun;25(3):151-7.
Shehata BM and Abramowsky CR. Alveolar Capillary Dysplasia in an Infant with Trisomy 21. Pediatric and Developmental Pathology 8, 696-700, 2005
Cerimele F, Battle T, Lynch R, Frank DA, Murad E, Cohen C, Macaron N, Sixby J, Smith K, Watnick RS, Eliopoulos A, Shehata BM, Arbiser JL. Reactive Oxygen Signaling and MAPK activation distinguish Epstein-Barr Virus (EBV)-positive versus EBV-negative Burkitt's lymphoma. Proc Natl Acad Sci U S A. 2005 Jan 4; 102 (1): 175-9.
Hunter, SBm Varma V, Shehata BM, Nolen JDL, Cohen C, Olsen JJ, Ou CY. Adolipoprotein D Expression in Primary Brain Tumors: Analysis by Quantitative PT-PCR in Formalin Fixed Paraffin Embedded Tissue. Journal of HIstochemistry & Cytochemistry 2005 Aug; 53(8):936-9.
Feldman AL, Berthold F, Arceci RJ, Abramowsky C, Shehata BM, Mann KP, Lauer SJ, Pritchard J, Raffeld M, Jaffe ES. Clonal Relationship between Precursor T-Lymphoblastic Leukaemia/Lymphoma and Langerhans Cell Sarcoma. The Lancet Oncology 2005 Jun; 6(6):435-7.
Folpe AL, Goldblum JR, Rubin BP, Shehata BM, Liu W, Dei Tos AP, and Weiss SW. Morphologic and Immunophenotypic Diversity in Ewing Family Tumor: A Study of 66 Genetically Confirmed Cases. American Journal of Surgical Pathology 2005 Jul; 29(8):1025-33.
Saad DF, Shehata BM, Gow KW, Wulkan MI: Pyloric Duplication in a Term Newborn. Pediatric Surgical Images 2005 Jul; 40(7):1209-10.
Schuetz AN, Rubin BP, Goldblum JR, Shehata BM, Weiss SW, Liu W, Wick MR, and Folpe AL. Intercellular Junction Protein Expression in Ewing Sarcoma/ Primitive Neuroectodermal Tumor: Additional Evidence of Epithelial Differentiation.( Accepted, Modern Pathology).
Black JO, White J, Abramowsky C, Shehata BM. Pathologic quiz case: Edema and diarrhea in a 2-year-old boy. Menetrier disease with cytomegalovirus gastritis. Arch Pathol Lab Med, 2004 Sep;128(9):e117-9.
Black JO, White J, Abramowsky C, Shehata BM. Pathologic quiz case: Edema and diarrhea in a 2-year-old boy. Menetrier disease with cytomegalovirus gastritis. Arch Pathol Lab Med, 2004 Sep;128(9):e117-9.
Gow K, Mayfield JK, Lloyd D, Shehata BM. Pseudoangiomatous stromal hyperplasia of the breast in two adolescent females. Am Surg 2004 Jul; 70 (7) 605-8.
Durham M, Gow KW, Shehata BM, Ricketts RR. Gastrointestinal stromal tumors arising from the stomach: A report of three children. Am J Ped Surg,vol 39,No 10,2004:pp1495-1499
Parast MM, Eudy G, Gow KW, Amin M, Shehata BM. A unique case of renal carcinoma with Xp11.2 Translocations/TFE3 gene fusion in a 3-year-old child, with coexistent von Hippel-Lindau gene mutation. Pediatr Dev Path, 2004 Jul-Aug 7 (4): 403-6.
Black JO, Rufforny-Doudenko I, Shehata BM. Pathologic quiz case: Third trimester placenta exhibiting infarction, Arch Pathol Lab Med 2003 Aug; 127 (8)::e340-2
Curtin WM, Shehata BM, Khuder SA, Robinson HB, Brost BCC. The feasibility of using histologic placental sections to predict newborn nucleated red blood cell counts. Obstet Gynecol, 2002 Aug; 100 (2):305-10.
Doudenko-Rufforny I, Sipp C, Shehata BM. Pathologic Quiz Case: A 30-year old woman with severe disseminated intravascular coagulation during delivery. Arch Pathol Lab Med Jul;126(7):869-70.
Shehata BM, Thomas JE, Doudenko-Rufforny I. Metastatic carcinoid to the conducting system: Is it a rare or merely unrecognized manifestation of carcinoid cardiopathy? Arch Pathol Lab Med 2002 Dec;126 (12):1538-40.
Matern D, Shehata BM, Shekhawat P, Strauss A, Bennett MJ, Rinaldo P. Placental floor infarction complicating the pregnancy of a fetus with long-chain 3-Hydroxyacyl-CoA Dehydrogenase (LCHAD) deficiency. Molecular Genetics and Metabolism 2001;72:265-268
Shehata BM, Patterson K, Thomas J, Barnett D, Dasu S, Robinson H. Histiocytoid cardiomyopathy: three new cases and a review of the literature. Ped Dev Path 1998 Jan-Feb;1(1):56-69.
Jabra AA, Fishman EK, Shehata BM, Perlman EJ. Localized persistent pulmonary interstitial emphysema: CT findings with radiographic pathologic correlation. AJR Am J Roentgenol 1997 Nov;169(5):1381-4.
Martin RW, Myers T, Shehata BM, Zemtsov A, Olson JL. Congenital absence of skin and blistering in a neonate. Bart's syndrome and mandibulofacial dysostosis. . Arch Dermatol 1995 Cot; 131(10):1197-1200
Perez-Benavides F, Park JM, Myers MK, Graham SC, Shehata BM. Sudden death in neonate with staphylococcal endocarditis. J Perinatol 1993 Jul-Aug; 13(4):285-7.
Boyd A, Neldner KH, Zemtsov A, Shehata BM. Photolocalized varicella. Journal of American Academy of Dermatology 1992;20:772-774.
Zemtsov A, Elks M, Shehata BM. Thyrotoxicosis presenting as generalized pruritic exfoliative Dermatitis and fever. Dermatology 1992; 184 (2): 157.
Vordermark JS, Shehata BM. The effects of ileocystoplasty on the development of renal failure in a rate model 5/6 nephrectomy. J Urol 1992 Aug; 148(2pt 2):566-70.
Novak R, Agamanolis DM, Dasu S, Igel H, Platt M, Robinson H, Shehata BM. Histologic analysis of placental tissue in first trimester abortions. Pediatric Pathology 1988;8:477-482.
Shehata BM. Benign Tumors with Myocyte Differentiation. WHO Classification of Tumors. Pathology & Genetics: Tumors of the Lung, Pleura, Thymus and Heart, Second Edition; 2014.
Shehata BM. Histiocytoid Cardiomyopathy. World Health Organization (WHO) Classification of Tumors, Pathology and Genetics of Lung, Pleura, Thymus, and Heart. In Press
Schniederjan M, Quigley P, Shehata BM, Viral Meningoencephalitis, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys; Published 2014.
Schniederjan M, Quigley P, Shehata BM. Bacterial Meningoencephalitis, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys; Published 2014.
Schniederjan M, Archer SR, Shehata BM. Protozoal Meningoencephalitis, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys; Published 2014.
Schniederjan M, Archer SR, Shehata BM. Fungal Meningoencephalitis, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Bunting CT, Quigley P. Hypoxic Ischemic Encephalopathy, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Elawabdeh N, Cundiff CA. Periventricular Leukomalacia, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Mina M. Naguib, Jenny Lin, and Geetika Khanna. Renal Tumors. Pediatric Neoplasia. In press
Shehata BM, Cundiff CA. Infarcts, Diagnostic Pathology: Placenta. Amirsys. In press
Shehata BM, Jactel SN, Elawabdeh N. Respiratory Syncytial Virus, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Jactel SN, Colvin EJ. Human Metapneumovirus, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Cooper CA, Colvin EJ, Pulmonary Venoocclusive Disease, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press
Shehata BM, Cone RY, Cooper CA. Congenital Alveolar Capillary Dysplasia, Diagnostic Pathology: Pediatric Non-Neoplastic, Amirsys. In press.
Shehata BM, Elawabdeh N, Cooper CA. Bronchogenic Cyst, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Cone BM, Bunting CT. Chronic Lymphocytic Thyroiditis, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Jordan HC, Archer SR. Hemorrhagic Necrosis of the Adrenal Gland, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Jordan HC, Colvin EJ. Stress Reactions in the Adrenal Gland, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Elawabdeh N. Germinal Matrix Hemorrhage, Diagnostic Pathology: Pediatric Non-Neoplastic. Amirsys. In press.
Shehata BM, Naguib, M. Renal Chapter in Tumors of Pediatric Population. Pediatric Neoplasm Textbook.
Shehata BM, Shulman SC. 29: Pathology and Differential Diagnosis. Chapter. Rare Tumors in Children and Adolescents. Springer-Verlag Berlin Heidelberg; 2012.
Shehata BM, Shulman SC. Chapter 3: Rare Tumors: Pathology and Biology Perspectives. Rare Tumors in Children and Adolescents. Springer-Verlag Berlin Heidelberg; 2012.
Shehata BM, Shulman SC. Histiocytoid Cardiomyopathy, Diagnostic Pathology: Pediatric Neoplasm. Amirsys; 2012.
Shehata BM, Lin J. Congenital Diaphragmatic Hernia with Emphasis on Embryology, Subtypes, and Molecular Genetics. Diaphragmatic Hernia: Diagnostics and Treatment. In-Tech Open Access Publisher.
Shehata BM, Steelman CK. The Heart. In: Husain AN, Stocker JT, eds. Atlas of Pediatric Pathology. 2011 Demos Medical Publishing.
Shehata BM, Burke AP. Benign Tumors with Myocyte Differentiation. WHO Classification of Tumors. Pathology & Genetics: Tumors of the Lung, Pleura, Thymus and Heart; 2004.
Robinson HB, Shehata BM. The Placenta: A Practical Guide to Evaluation and Interpretation. FDE, Ltd.; 1995.