Pathology Faculty Member

More information on...

  • Home
  • Training
  • Research
  • Clinical Services
  • Expert Consultation
  • Faculty
  • Contact Information:

    Experimental Pathology
    Whitehead Building, First Floor
    Atlanta, GA 30322
    404 727-9397 Phone

    For an expert Pathology consultation,
    or to send a specimen, call:


    Dominique A Weber, PhD

    Experimental Pathology

    Assistant Professor
    Pathology & Laboratory Medicine

    Pathology Faculty Photo

    Pathology Division(s):
    Experimental Pathology

    Email Address:

    Education:   University of Paris, France, - 1967

    Ph.D.   Columbia University, New York, - 1989

    Honors / Awards:

    1989-1992 Cancer Research Institute Postdoctoral Fellowship, 1989-1992

    Selected Publications:

    Published and Accepted Research Articles -

    Jensen PE, Sullivan BA, Reed-Loisel LM, Weber DA. (2004) Qa-1, a nonclassical class I histocompatibility molecule with roles in innate and adaptive immunity. Immunol Res.;29(1-3):81-92.

    Miller JD, Weber DA, Ibegbu C, Pohl J, Altman JD, Jensen PE. (2003) Analysis of HLA-E peptide-binding specificity and contact residues in bound peptide required for recognition by CD94/NKG2.(2003) J Immunol. 171(3):1369-75.

    D.A.Weber, A. Attinger, C.C. Kemball, J.L. Wigal, Jan Pohl, Yi Xiong, E.L. Reinherz, H. Cherouter, M. Kronenberg, and P.E. Jensen (2002) Peptide-Independent Folding and CD8aa Binding by the Nonclassical Class I Molecule, Thymic Leukemia Antigen J. Immunol. 169: 5708-5714

    X.Chen, O. Laur, T. Kambayashi, S. Li, R.A. Bray, D.A. Weber, L. Karlsson and P.E. Jensen (2002) Regulated Expression of Human Histocompatibility Leukocyte Antigen (HLA)-DO During Antigen-dependent and Antigen-independent Phases of B Cell Development. J. Exp. Med. 195: 1053-1062

    Sullivan, B.A., P. Kraj, D.A. Weber, L. Ignatowicz, and P.E. Jensen. Positive selection of a Qa-1-restricted T cell receptor with specificity for insulin. 2002 Immunity, , 17:95-105.

    D.A. Weber, C.T. Dao, J. Jun, J. L. Wigal and P.E. Jensen. (2001) Transmembrane Domain-Mediated Colocalization of HLA-DM and HLA-DR Is Required for Optimal HLA-DM Catalytic Activity. J. Immunol. 167: 5167-5174

    Dao C.T., Weber D.A., Jensen P. E. Analysis of two acidic P6 pockets residues in the pH dependency if peptide binding by I-Ek. (2001) Molecular Immunology 38: 1139-1149

    P.E. Jensen, D.A.Weber, W.P. Thayer, L.E. Westerman and C.T. Dao. Peptide Exchange in MHC molecules. (1999), Immunological Reviews, Vol.172, 229-238.

    P.E. Jensen, D.A.Weber, W.P. Thayer, X. Chen and C.T. Dao. (1999) HLA-DM and the MHC Class II Antigen Presentation Pathway. Immunologic Research 20/3: 195-205

    Thayer, W.P., Ignatowicz, L., Weber, D.A. and P.E. Jensen. (1999) Class II-Associated Invariant chain Peptide-independent binding of invariant chain to class II MHC molecules. J. Immunol. 162: 1502-1509

    Sherman, M.A., Weber, D.A., Spotts, E.A., Moore, J.C., and Jensen, P.E. (1997) Inefficient peptide binding by cell-surface class II MHC molecules. Cellular Immunology 182:1-11.

    Runnels, H.A., Weber, D.A, Tan, J.T. and Jensen, P.E. (1997) Intact Proteins Can Bind to Class II Histocompatibility Molecules with High Affinity. Molecular Immunology 34:471-480.

    D.A. Weber, B.D. Evavold, P.E. Jensen. (1996). Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM. Science 274: 618-620.

    K.M. Soreng, D.A. Weber, H.Joshi, J.C. Moore and P.E. Jensen. (1995) A Role for Microfilaments but not Microtubules in Processing Solubles Antigens. Cellular Immunology 165, 1-10.

    D.A. Weber, Terrel, N.K., Zhang, Y., Strindberg, G., Martin, J., Rudensky, A., and Braunstein, N.S. (1995). Requirement for Peptide in Alloreactive CD4+ T Cell Recognition of Class II MHC Molecules. J. Immunol. 154: 5154-5163.

    Sherman, M.A., Weber, D.A., and Jensen, P.E. (1995) Peptide Binding to Class II MHC Molecules is Catalyzed by DM. (1995) Immunity 3 no2, 197-205.

    N.S. Braunstein, D.A. Weber, Xiao-Cun Wang, E. O. Long and D. Karp.Sequences in both class II MHC alpha and beta chains contribute to the binding of the superantigen TSST-1. 1992. J. Exp. Med. 175:1301-1305.

    D.A. Weber, L. Buck, T. M. Delohery, N. Agostino, and B. Pernis. Class II molecules are spontaneously internalized in acidic endosomes by activated B cells. 1990. J. Mol. Cell. Immunol. 4:255-268.

    B. Pernis and D. A. Weber. Cell biology of Antigen Presentation by B cells, 1989. In: B Lymphocytes: Function and Regulation. Contr. Microbiol. Immunol. Ed. P. del Gercio. Karger AG, Basel. Vol.11, pp. 27-42.

    L. Guarini, D.A. Weber, and B. PernisDifferential endocytosis of IgM and IgD in murine B cells lines. 1989. . Cellular Immunol. 123:456-461.